The influence of the polymerization approach on the catalytic performance of novel porous poly (ionic liquid)s for green synthesis of pharmaceutical spiro-4-thiazolidinones

Abstract

Sustainable synthesize of a new mesoporous poly (ionic liquid) as acid–base bifunctional catalyst for environmental being preparation of monospiro derivatives has been developed.

Ultrasound-Engineered fabrication of immobilized molybdenum complex on Cross-Linked poly (Ionic Liquid) as a new acidic catalyst for the regioselective synthesis of pharmaceutical polysubstituted spiro compounds

“…The vinyl functionalized Co 3 O 4 NPs were obtained via mixing NPs (1 g) and 3-(trimethoxysilyl) propylmethacrylate (MPS) (10 mmol) in EtOH under ultrasound condition (about 2 h). The same preparation method was carried out for 24 h under reflux condition according to the reported work [29] . Finally, to separate the MPS, coated Co 3 O 4 @MPS was separated by centrifugation (6000 rpm, 5 min) and washed with EtOH to eliminate the unreacted compounds.…”

“…Polymerization of aminopropyl-3-vinylimidazolium bromide [AVIM]Br (IL), induced by ACPA in the H 2 O to form the porous ionic polymer network, was conducted. Ionic liquid was prepared according to our previous reported protocol [29] . Typically, vinyl functionalized Co 3 O 4 NPs (0.5 g), (IL) (0.005 mol, 0.45 g), and crosslinker (N,N’-Methylenebis acrylamide) were dissolved into 10 ml deionized water and then submitted to an ultrasonic agitation for 15 min.…”

A review on advances in synthetic methodology and biological profile of spirothiazolidin‐4‐ones

“…Elyasi and coworkers [36], in the year 2020, designed a new hypercrosslinked polymerized ionic liquids and immobilized on vinyl functionalized Co 3 O 4 nanoparticles to form Co 3 O 4 @crosslinked p[AVIM]Br 4 . Polymerized ionic liquids bear the dual characteristics of ionic liquids as well as of traditional polymers.…”

Recent advances on the nanocatalyzed synthesis of 1,3‐thiazolidines

“…Elyasi et al carried out the multicomponent reaction of isatins, primary amines, and thioglycolic acid to synthesize spiro-4-thiazolidinone using MPS coated Co 3 O 4 NPs at room temperature under ultrasound irradiation (Scheme 30). [37] A mixture of Co 3 O 4 MNP in ethanol was prepared. Then ammonia solution was added.…”