The Influence of the Preoperative Status on the Risk of Postoperative Complications After Cytoreductive Surgery for Advanced-stage Ovarian Cancer

Abstract

Background/Aim: The aim of this study was to analyze the influence of preoperative status on the risk of developing further postoperative complications after debulking surgery for advanced-stage ovarian cancer. Patients and Methods: A total of 80 consecutive patients submitted to surgery between 2014 and 2019 for advancedstage ovarian cancer were retrospectively reviewed. Results: Among the 80 cases there were seven patients who developed serious postoperative complications requiring reintervention. Among these cases it seems that association of obesity, poor nutritional status (defined as a lower than 3.5 g/dl serum albumin level) and elderly age were significantly associated with the risk of developing further complications. Conclusion: When selecting the candidates for debulking surgery for advanced-stage ovarian cancer attention should be focused on excluding cases presenting such preoperative risk factors in order to decrease the postoperative morbidity.

Right Upper Abdominal Resections in Advanced Stage Ovarian Cancer

“…Tumor spread at this level has been described in half of patients with advanced stage ovarian cancer, with particular sensitivity in the right diaphragm compared to the left diaphragm (11,22,23). The real extent of the disease at the level of the diaphragm is frequently underestimated during the preoperative studies (24)(25)(26). For this reason, oncogynecologists dealing with advanced stage ovarian cancer patients should be prepared to complete the debulking process at this level as well, with the extent of the resection being proportional to the amount of tumoral nodules identified (27).…”

A Zn(ii)–organic cage with semirigid ligand for solvent-free cyanosilylation and inhibitory effect on ovarian cancer cell migration and invasion ability via regulating mi-RNA16 expression

“…For example, Li and his colleagues have reported the ringopening of styrene oxide promoted via the MOP [15]; Wang and co-workers have applied an In(III)-MOP as the heterogeneous catalyst in Strecker reaction of aminonitriles and CO 2 cycloaddition [16]. In this research, 4 (1, L = 4,4′,4″-(benzene-1,3,5-triyltris(oxy))tribenzoate), the metal-organic cage, was triumphantly produced through the reaction between H 3 L ligand and Zn (NO 3 ) 2 •6H 2 O in the mixed solvent of DMF and water. The complex 1's heterogeneous catalytic activities for the cyanosilylation of aldehydes under the solvent-free conditions were studied, which reveals that the removal of coordination solvents could greatly improve the catalytic activities.…”

“…The complex 1's colorless bulk crystals can be acquired via the solvothermal reaction between H 3 L and Zn (NO 3 ) 2 •6H 2 O in 1,4-dioxane and DMF mixed solvents at 85°C for 24 h, and its chemical formula was 4 according to the analysis of element and the single crystal diffraction of X-ray results. Complex 1 was insoluble in some common organic solvents such as the DMF, EtOH, and MeOH, which indicates that it might be applied as the heterogeneous catalyst for the organic reactions.…”

“…More and more studies have shown that changes in mi RNA expression levels are related to the pathogenesis and progression of a variety of human malignancies, for instance, ovarian cancer, cervical cancer, as well as colorectal cancer [2,3]. The miRNA abnormal expression in ovarian cancer is closely related to its occurrence, development, metastasis, drug resistance, and prognosis [4]. It is expected to become a marker for early diagnosis and prognosis of ovarian cancer and provide a new clinical analysis for chemotherapy resistance and personalized treatment ideas.…”

A review of robotic surgery in the management of recurrent ovarian carcinoma: indication and techniques

“…Performing these complex radical dissections has traditionally required open laparotomy. The postoperative morbidity from open secondary cytoreductive surgery rate has been reported to be between 32.5% and mortality rate at 2.5% [14]. The morbidity from robotic-assisted secondary debulking is associated with less blood loss, shorter hospitalization, and lower complication rates than open secondary debulking [15,16].…”