The influence of the various central metals on photophysical and photochemical properties of benzothiazole-substituted phthalocyanines

Nas, Asıye; Dilber, Gülsev; Durmuş, Mahmut; Kanteki̇n, Hali̇t

doi:10.1016/j.saa.2014.06.135

Cited by 24 publications

(8 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[17][18][19][20][21][22][23][24][25][26][27] These substituted phthalocyanines can be highly efficient photosensitizers of singlet oxygen due to dual or synergistic therapeutic effect. [28,29] However, only a few works devoted to phthalocyanines [30][31][32] and porphyrin [33] containing pyrazole substituents are known.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Isolation of 2,9,17,23-Tetrakis[(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy]phthalocyanine and Its Magnesium(II) and Zinc(II) Complexes

Ziminov¹,

Furman²,

Borisov³

et al. 2016

MHC

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Synthesis and Isolation of 2,9,17,23-Tetrakis[(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy]phthalocyanine and Its Magnesium(II) and Zinc(II) Complexes

Ziminov¹,

Furman²,

Borisov³

et al. 2016

MHC

View full text Add to dashboard Cite

show abstract

“…[18][19][20] There are some studies in the literature which reported photosensiter properties of different phthalocyanines containing benzothiazole groups. [21,22] But in this paper, it was planned to prepare novel non-peripherally benzothiazole substituted phthalocyanines as photosensitizer compounds which can have potential for PDT apllications. To improve the pharmacological properties of photosensitizers benzothiazole groups were attached to the non-peripherally substitution positions of phthalocyanine ring.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, Characterization, Photophysical and Photochemical Properties of Novel Phthalocyanines

Demirbaş

2020

ChemistrySelect

View full text Add to dashboard Cite

The benzothiazole substituted phthalonitrile (3) and nonperipherally tetra benzothiazole substituted metal-free (4), zinc (II) (5) and lead(II) phthalocyanine (6) complexes were prepared. The compounds (3-6) were characterized by IR, NMR, UV-Vis and mass spectroscopy data. After synthesis, photochemical and photophysical parameters of the compounds (4-6) were analyzed to determine photosensitizer performance of them for PDT applications. Firstly, the most suitable solvent for compounds (4-6) was found by aggregation studies. Then, fluorescence properties were measured in DMF at 1x10 À 6 M. Singlet oxygen properties were measured in DMF by using 1,3diphenylisobenzofuran (DPBF) as a singlet oxygen quencher. Photodegradation properties were measured under light irradiation in DMF at 1x10 À 5 M. The zinc(II) phthalocyanine (5) had the highest singlet oxygen production capacity (Φ~= 0.62), fluorescence (Φ F = 0.25) and photodegradation quantum yield (Φ d = 3.28x10-4). The results showed that zinc(II) phthalocyanine (5) has potential for photodynamic therapy applications.

show abstract

“…Thiazoles can be illustrated by a large number of drugs in the market such as the Ritonavir (antiretroviral drug), Sulfathiazole (antibacterial drug) and Tiazofurin (antineoplastic drug) Figure . Thiazole nucleus also finds its applications in various other fields including polymers, liquid crystals, photonucleases, fluorescent dyes ,. Thiazole skeleton has a strong electron donor unit usually with varying HOMO or LUMO values, which allows efficient lowering of both frontier orbital levels, while keeping the energy band gap almost unchanged,, which is attributed to organic light emitting diodes (OLEDs) …”

Section: Introductionmentioning

confidence: 99%

Microwave‐Expedited Green Synthesis, Photophysical, Computational Studies of Coumarin‐3‐yl‐thiazol‐3‐yl‐1,2,4‐triazolin‐3‐ones and Their Anticancer Activity

et al. 2018

View full text Add to dashboard Cite

Mild and efficient synthesis of 5‐methyl‐4‐[(2Z)‐4‐(2‐oxo‐2H‐chromen‐3‐yl)‐2‐(4‐arylimino)thiazol‐3(2H)‐yl]‐2‐(4‐aryl)‐2H‐1,2,4‐triazol‐3(4H)‐ones 7(h–s) has been developed using microwave assisted multicomponent route. The molecular structures of these novel compounds were characterized and the photophysical and thermal properties were investigated elaborately using absorption, fluorescence, fluorescence decay lifetimes and thermo gravimetric analysis. Solvatochromism was studied as a function of polarity of the solvents. The ground and excited states of electronic geometric optimizations were computed using density functional theory (DFT and TD‐DFT). The orientation of atomic orbitals and their energies were supported by HOMO‐LUMO calculations. Electrostatic potential (ESP) maps indicated the electron density predicting the reactive sites. Compounds 7(h–s) were docked into the epidermal growth factor receptor (EGFR) tyrosine kinase domain which formed a stable complex with good C‐score values. The title compounds were evaluated for their anticancer activity against A549, MDA‐MBA‐231, HeLa and K562 cancer cell lines which showed sensitivity against most of the tested compounds.

show abstract

The influence of the various central metals on photophysical and photochemical properties of benzothiazole-substituted phthalocyanines

Cited by 24 publications

References 32 publications

Synthesis and Isolation of 2,9,17,23-Tetrakis[(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy]phthalocyanine and Its Magnesium(II) and Zinc(II) Complexes

Synthesis and Isolation of 2,9,17,23-Tetrakis[(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy]phthalocyanine and Its Magnesium(II) and Zinc(II) Complexes

Synthesis, Characterization, Photophysical and Photochemical Properties of Novel Phthalocyanines

Microwave‐Expedited Green Synthesis, Photophysical, Computational Studies of Coumarin‐3‐yl‐thiazol‐3‐yl‐1,2,4‐triazolin‐3‐ones and Their Anticancer Activity

Contact Info

Product

Resources

About