The influence of two different dental local anaesthetic solutions on the haemo-dynamic responses of children undergoing restorative dentistry: a randomised, single-blind, split-mouth study

Meechan, J G; Cole, Ben; Welbury, Richard

doi:10.1038/sj.bdj.4801015

Cited by 23 publications

(25 citation statements)

References 15 publications

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“…To reduce plasma levels of the local analgesic and to enhance the analgesic effect, the use of a vasoconstrictor is recommended (Lipp et al 1993; Meechan et al 1994; Yagiela 1995), although, the vasoconstrictor may produce its own adverse side-effects (Meechan et al 2001; Santos et al 2007). To minimise those and to balance risk and benefit, a reduction of the vasoconstrictor in paediatric dentistry may be of value.…”

Section: Discussionmentioning

confidence: 99%

Epinephrine-reduced articaine solution (1:400,000) in paediatric dentistry: a multicentre non-interventional clinical trial

Kämmerer

Krämer

Esch³

et al. 2013

Eur Arch Paediatr Dent

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AimIn paediatric dentistry, epinephrine may contribute to systemic and local side-effects. On the other hand it is necessary to provide good and safe local analgesia. Therefore, an articaine solution with reduced epinephrine concentration was tested in a clinical setting.MethodsIn a non-interventional clinical study, dental treatment was performed in children and adolescents (4–17 years). For local analgesia, articaine 4 % plus epinephrine 1:400,000 was used in the technique chosen by the dentist. Efficacy and tolerance as well as duration of soft tissue analgesia and side-effects were evaluated.Results999 patients (50.5 % male, 49.5 % female) with a mean age of 7.9 (SD 2.34) years were treated. Two hundred seventy six patients (27.6 %) received sedation prior to treatment. The mean treatment time was 15 min (SD 10). In 93.5 % of cases, initial local analgesia was sufficient to perform the planned treatment. In 99 % of cases (n = 989) the planned treatment could be completed. A second injection was necessary in 6.5 % of cases. A mean duration of soft tissue analgesia of 2.19 h (SD 1.01) was seen. Slight side-effects occurred in 3.1 % of subjects.ConclusionsDue to high efficacy, tolerance and safety, the articaine 4 % solution with the reduced epinephrine concentration (1:400,000) was a safe and suitable drug for paediatric routine treatment.

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Section: Discussionmentioning

confidence: 99%

Epinephrine-reduced articaine solution (1:400,000) in paediatric dentistry: a multicentre non-interventional clinical trial

Kämmerer

Krämer

Esch³

et al. 2013

Eur Arch Paediatr Dent

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“…Many studies have evaluated the physiological alterations related to dental anxiety, such as heart rate; 7,13,14 blood pressure; 13–15 oxygen saturation; 16 breathing; 17 Palmar Sweat Index; basal skin response; galvanic skin response; muscle tension; 17 and skin temperature 18 …”

Section: Discussionmentioning

confidence: 99%

“…Some studies 15,19,20 observed that patients had higher heart rates before dental treatment, while Ferro and Docimo 21 showed the opposite. Some studies reported an increased heart rate before, 13,22 during, 23 or after local anesthesia 14,16 . According to Brand and Abraham‐Inpijn, 24 the heart rate increases found during an injection of local anesthesia may be related to the use of vasoconstrictors and, in some cases, heart rate may decrease when local anesthesia is not used.…”

Section: Discussionmentioning

confidence: 99%

“…Many studies have evaluated the physiological alterations related to dental anxiety, such as heart rate; 7,13,14 blood pressure; [13][14][15] oxygen saturation; 16 breathing; 17 Palmar Sweat Index; basal skin response; galvanic skin response; muscle tension; 17 and skin temperature. 18 Some studies 15,19,20 observed that patients had higher heart rates before dental treatment, while Ferro and Docimo 21 showed the opposite.…”

Section: Discussionmentioning

confidence: 99%

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Behavioral and physiological changes in children with Down syndrome using mechanical and chemomechanical (Carisolv™) caries removal methods

Guaré

Ciamponi

Romano

2008

Special Care in Dentistry

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This study compared behavioral and physiological changes during caries removal in children with Down syndrome when using a chemomechanical caries removal technique (Carisolv) and a conventional method of caries removal. Twenty children (ASA class 1) between 5 and 12 years of age participated in the study; 10 subjects had Down syndrome and 10 were healthy controls. The behavioral and physiological assessments were carried out during five stages of dental treatment: (1) 5 minutes before local anesthesia; (2) during local anesthesia; (3) during caries removal; (4) immediately after restoration; and (5) 5 minutes after the end of the treatment. The caries removal step resulted in the greatest behavioral and physiological changes. Except for oxygen saturation, statistically significant differences in heart rate (p<0.05) were recorded between children with Down syndrome and the control children.

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“…Transient sinus tachycardia after local anesthesia with solutions containing epinephrine has been described in adults and children (4,5). Absorption from the injection site is responsible for these side effects.…”

mentioning

confidence: 99%

Unexpected postoperative tachycardia in a patient with 22q11 deletion syndrome after multiple dental extractions

Passariello¹,

Perkins²

2005

Pediatric Anesthesia

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The influence of two different dental local anaesthetic solutions on the haemo-dynamic responses of children undergoing restorative dentistry: a randomised, single-blind, split-mouth study

Cited by 23 publications

References 15 publications

Epinephrine-reduced articaine solution (1:400,000) in paediatric dentistry: a multicentre non-interventional clinical trial

Epinephrine-reduced articaine solution (1:400,000) in paediatric dentistry: a multicentre non-interventional clinical trial

Behavioral and physiological changes in children with Down syndrome using mechanical and chemomechanical (Carisolv™) caries removal methods

Unexpected postoperative tachycardia in a patient with 22q11 deletion syndrome after multiple dental extractions

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