The influence of UV irradiation on the biological properties of MAO-formed ZrO2

Zhang, Ziqi; Wang, Kunzheng; Bai, Chuanyi; Li, Xiaobin; Dang, Xiaoqian; Zhang, Chen

doi:10.1016/j.colsurfb.2011.08.020

Cited by 25 publications

(14 citation statements)

References 37 publications

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“…However, the latter two studies did not use an osteoblast-differentiation medium for the cell culture, excluding thereby a component needed for proper osteoblast differentiation and matrix mineralisation under in vitro conditions (Coelho and Fernandes, 2000;Eijken et al, 2006). Except for the latter two studies, the overall trend of UV-induced biological enhancement on zirconia is in agreement with previous reports (Att et al, 2009c;Watanabe et al, 2012;Zhang et al, 2012). Nevertheless, the extent to which the behaviour and response of osteoblasts are enhanced seems to be different.…”

Section: T Tuna Et Al Photofunctionalisation Of Zirconia Surfacessupporting

confidence: 81%

“…In light of these findings, it is of interest to investigate as to how far UV-light treatment can influence the bioactivity of a new type of roughened zirconia. To the authors' knowledge, a number of in vitro studies investigated the effect of UV light treatment on the bioactivity of zirconia-based materials (Altmann et al, 2013;Han et al, 2009;Watanabe et al, 2012;Zhang et al, 2012). However, due to different study designs as well as controversial results, no clear conclusions can be drawn about the effect of UV treatment on zirconia surfaces.…”

Section: Wwwecmjournalorg T Tuna Et Al Photofunctionalisation Of Zmentioning

confidence: 99%

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Effect of ultraviolet photofunctionalisation on the cell attractiveness of zirconia implant materials

Tuna

Wein²,

Altmann³

et al. 2015

eCM

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Ultraviolet (UV) light treatment of implant surfaces has been demonstrated to enhance their bioactivity significantly. This study examined the effect of UV treatment of different zirconia surfaces on the response of primary human alveolar bone-derived osteoblasts (PhABO). Disks of two zirconia-based materials with two different surface topographies (smooth, roughened) were exposed to UV light. Qualitative and quantitative assessment of PhABO on zirconia surfaces, by means of immunofluorescence, scanning electron microscopy and DNA quantification at 4 and 24 h revealed a higher number of initially attached osteoblasts on UV-treated surfaces. Cell area and perimeter were significantly larger on all UV-treated surfaces (p < 0.05). The proliferation activity was significantly higher on both roughened UV-treated surfaces than on untreated samples at day 3 of culture (p < 0.05). The expression levels of collagen I, osteopontin and osteocalcin at day 14 and alkaline phosphatase activity at day 7 and 14 of culture period were similar among UV-treated and untreated surfaces. Alizarin-Red-Staining at day 21 demonstrated significantly more mineralised nodules on UV-treated samples than on untreated samples. Contact angle measurements and X-ray photoelectron spectroscopy showed that UV light transformed zirconia surfaces from hydrophobic to (super-) hydrophilic (p < 0.05) and significantly reduced the atomic percentage of surface carbon. The results showed that UV light pre-treatment of zirconia surfaces changes their physicochemical properties and improves their attractiveness against PhABO, primarily demonstrated by an augmented cell attachment and spreading. This may result in faster healing and better bone-to-implant contact of zirconia implants in vivo following such a pre-treatment.

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Section: T Tuna Et Al Photofunctionalisation Of Zirconia Surfacessupporting

confidence: 81%

Section: Wwwecmjournalorg T Tuna Et Al Photofunctionalisation Of Zmentioning

confidence: 99%

Effect of ultraviolet photofunctionalisation on the cell attractiveness of zirconia implant materials

Tuna

Wein²,

Altmann³

et al. 2015

eCM

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“…It has excellent chemical, physical, electrical, mechanical, optical, dielectric, and thermal properties such as high melting point, high resistance to thermal shock, good chemical stability, low electrical conductivity, high dielectric constant, high refractive index, large optical band gap, low optical loss and high transparency in the visible and near infrared region, excellent wear resistance, and biocompatibility [1][2][3][4]. These properties make zirconia valuable in a number of applications in fuel-cell technology, catalysis, in the fields of structural materials, gas sensors, protective coating for optical mirrors and filters, etc.…”

Section: Introductionmentioning

confidence: 99%

Zirconia films formed by plasma electrolytic oxidation: Photoluminescent and photocatalytic properties

et al. 2015

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“…Today, biofunctionality studies compare adhesion and differentiation of osteogenic cells on titanium and zirconia surfaces 12) . Microarrays have also been used to study MG63 grown on zirconia discs 13) , and the response of osteogenic cells to zirconia surface treatment by ultraviolet or laser irradiation has been reported 14,15) . Still, studies comparing the impact of implant raw materials and surface modifications of biomaterials including titanium and zirconia are rare.…”

Section: Introductionmentioning

confidence: 99%

Acid and alkali etching of grit blasted zirconia: Impact on adhesion and osteogenic differentiation of MG63 cells in vitro

et al. 2012

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There is a need for evaluating zirconia surface modifications and their potential impact on the biological response of osteogenic cells. Grit blasted zirconia discs were either left untreated or underwent acid or alkaline etching. Adhesion and osteogenic differentiation of MG63 cells was determined after one week of culture. The macro-scaled roughness of the grit blasted zirconia discs, independent of the surface treatment, was within a narrow range and only slightly smoother than titanium discs. However, the alkaline-and acid-etching led to an increase of the micro-roughness of the surface. The surface modifications had no effect on cell spreading and did not cause significant change in the expression of differentiation markers. Thus, in this respective setting, morphologic changes observed upon treatment of grit blasted zirconia discs with acid or alkaline do not translate into changes in MG63 cell adhesion or differentiation and are comparable to findings with anodized titanium discs.

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The influence of UV irradiation on the biological properties of MAO-formed ZrO2

Cited by 25 publications

References 37 publications

Effect of ultraviolet photofunctionalisation on the cell attractiveness of zirconia implant materials

Effect of ultraviolet photofunctionalisation on the cell attractiveness of zirconia implant materials

Zirconia films formed by plasma electrolytic oxidation: Photoluminescent and photocatalytic properties

Acid and alkali etching of grit blasted zirconia: Impact on adhesion and osteogenic differentiation of MG63 cells in vitro

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