The Influence of Zinc Sulfate Supplementation on the Growth of School Age Children in Villages Around Shiraz 2002, 2003

., P. Dehbozorgi; Mohseni, P; Mazloom, Zohreh

doi:10.3923/jms.2007.690.693

Cited by 7 publications

(4 citation statements)

References 10 publications

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“…Additional 17 articles were excluded by full text for the following reasons: not being clinical trials [ 18 – 20 ], do not use zinc alone [ 21 – 25 ], non-healthy subjects [ 26 – 28 ], under 2 years [ 29 – 33 ], and zinc supplementation of mothers [ 34 ]. Finally, eight eligible RCTs remained for inclusion in the current systematic review and meta-analysis [ 35 – 42 ].…”

Section: Resultsmentioning

confidence: 99%

“…The result of the risk of bias is shown in Table 2 . Only two studies [ 36 , 37 ] could be considered high-quality studies, two RCTs [ 42 , 43 ] were of moderate quality and others had low-quality.…”

Section: Resultsmentioning

confidence: 99%

“…The effects of zinc supplementation on weight were evaluated in seven research, including 1488 people [ 35 , 36 , 38 – 42 ]. Considering the presence of high heterogeneity between studies ( I 2 = 95.9, P < 0.001), the random-effect model was used.…”

Section: Resultsmentioning

confidence: 99%

“…The results of the sensitivity analysis revealed that the magnitude of the overall effect regarding the association between zinc supplementation and height, WAZ, and HAZ did not depend on a single study. However, in terms of weight, the total impact size depended on some studies [ 35 – 42 ]. As a result, when those studies were disregarded, a substantial positive correlation between zinc supplementation and weight was discovered.…”

Section: Resultsmentioning

confidence: 99%

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The effect of zinc supplementation on anthropometric measurements in healthy children over two years: a systematic review and meta-analysis

Monfared,

Salehian,

Nikniaz

et al. 2023

BMC Pediatr

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Background Zinc deficiency is one of the most important micronutrient deficiencies in children that can affect the children’s growth pattern. In this regard, different studies were conducted to assess the effect of zinc supplementation on growth patterns in healthy children. To the best of our knowledge, no systematic review has summarized the results of these studies. So, in the present study, we systematically reviewed the result of the studies that assessed the effect of zinc supplementation on anthropometric parameters in healthy, over 2-year-old children. Methods A systematic search was carried out in PubMed, Scopus, and Web of Science from inception to November 2021. Data were pooled using the random-effects method and were expressed as weighted mean difference (WMD) and 95% confidence intervals (CI). Results The pooled results of eight studies, including 1586 participants, showed that zinc supplementation significantly increases height [(WMD): 0.9, 95% CI: (0.27, 1.52), p < 0.001], weight [(WMD): 0.51, 95% CI: (0.06, 0.97), p < 0.001], height for age (HAZ) [(WMD): 0.07, 95% CI: (0.03, 0.10), p < 0.001]. Also, meta-regression analysis did not reveal any significant association between dose and duration of intervention and anthropometric parameters. Conclusion The present study demonstrates the beneficial effects of zinc supplementation on weight, height, and HAZ.

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