The influences of polycaprolactone-grafted nanoparticles on the properties of polycaprolactone composites with enhanced osteoconductivity

Synthesis and corrosion behavior of a hybrid bioceramic-biopolymer coating on biodegradable Mg alloy for orthopaedic implants

“…However, the FTIR spectrum of the PCL/OCP/HA composite sample include: (1) e(CH 2 )e skeletal group in the range of 2978e2812 cm À1 and 1465e1226 cm À1 ; (2) C]O band centred at 1612 cm À1 ; and (3) CeO groups in the range 1253e1114 cm À1 . The strong absorption of the C]O bond was indicative of an aliphatic ester of PCL on the surface [20]. The FTIR spectrum further confirmed the formation of a OCP/HA and PCL/OCP/HA layered film.…”

Nanomaterials: The Next Step in Injectable Bone Cements

“…The chemical composition of the nanoparticles appears to be an important factor in determining the biological capabilities of an IBC nanocomposite. Hong et al demonstrated increased adhesion and differentiation of bone marrow stem cells cultured on PCL-nanohydroxyapatite (nHA) composites compared with those on PCL with dispersed SiO 2 , TiO 2 and SrO nanoparticles [79]. By contrast, PCL composites with SrO nanoparticles showed poor cytocompatibility, while PCL-SiO 2 and PCL-TiO 2 nanocomposites showed no reduction in cell viability compared with pure PCL [79].…”

“…Hong et al demonstrated increased adhesion and differentiation of bone marrow stem cells cultured on PCL-nanohydroxyapatite (nHA) composites compared with those on PCL with dispersed SiO 2 , TiO 2 and SrO nanoparticles [79]. By contrast, PCL composites with SrO nanoparticles showed poor cytocompatibility, while PCL-SiO 2 and PCL-TiO 2 nanocomposites showed no reduction in cell viability compared with pure PCL [79]. Sr 2+ ions can also be used to modify inorganic nanoparticles such as TiO 2 in order to improve osteoblast proliferation on PMMA [80].…”

“…Upon sufficient agglomeration, these particles become like microparticles, acting as larger crack initiation sites that reduce their strength [106], thereby reducing their surface roughness [100] and their ability to release bioactive ions [87]. Agglomeration is usually reduced or prevented by modifying the surface of the nanomaterial through mineralization [52,53], pregrafting with the matrix material [79,109] and silanization [99,108]. Results in these types of modifications demonstrated better distribution of the nanoparticles compared with untreated nanoparticles.…”

Elaboration and characterization of a multifunctional silane/ZnO hybrid nanocomposite coating

“…Various types of metal oxide fillers such as ZrO 2 , TiO 2 , SiO 2 have been incorporated into polymers according to the required properties [6][7][8]. Among the various types of available nanoparticles, the nanosized zinc oxide, well known as multifunctional inorganic nanofiller, has reached a greater interest due to its physical and chemical properties, such as a low dielectric constant, a wide band gap of 3.37 eV at room temperature and a high exciton binding energy of approximately 60 meV, which is in the UV region.…”