The Infrared Spectra of Acridines

Can Zeolite-Supporting Acridines Boost Their Anticancer Performance?

“…A skeletal C-C stretching vibrations of benzene and pyridine units in Acr could be seen in the 1625-1475 region, while the remaining bands are ascribed to C-H vibrations [ 33 ]. The most intense acridine band, not overlapped with the zeolite bands, at about 732 cm −1 , corresponds to C-H out-of-plane bending vibration, and it is visible in the spectrum of the impregnated zeolite sample Acr/Y, but it is shifted by 10 cm −1 towards higher wavenumbers.…”

Octahydroacridine thin films grown by matrix-assisted pulsed laser evaporation for non linear optical applications

“…Acridine (C 13 H 9 N) is a stable, weakly basic compound, structurally related to anthracene (C 14 H 10 )w i t ho n eo ft h e central CH groups replaced by nitrogen [1,2].P u r ea c r i d i n e was first isolated in 1871 by Carl Gräbe and Heinrich Caro, as it naturally occurs in coal tar. Its derivatives are a class of materials with a large area of applications, most of them known human carcinogens, causing frameshift mutations by incorporating into the DNA and creating an additional base on the opposite strand [1][2][3][4][5]. They have been widely used as antibacterial and antiprotozoal agents, e.g.…”

“…One such compound is 1,2,3,4,5,6,7,8-octahydroacridine (C 13 H 17 N) or OHA, a white crystalline solid that is less toxic compared to acridine [11,12]. OHA and its derivatives are of great interest as they play an important role in the preparation of agrichemicals, alkaloids, dyes, medicines, drugs and other biologically active compounds with intriguing pharmacological and therapeutic properties in cancer and Alzheimer's disease treatments, and advanced functional materials precursors [1,2,13,14].T o d a y , OHA can be easily synthesized by different routes [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30], making it an economically attractive candidate for various applications due to its excellent price/quality ratio. Among these applications, non-linear optical (NLO) properties that may arise from particularities of the OHA molecule (i.e.…”

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We report on the thin film growth of 1,2,3,4,5,6,7, by matrixassisted pulsed laser evaporation (MAPLE), starting from a frozen solution of 1% OHA dissolved in methanol and using a Nd:YAG laser emitting at 266 nm wavelength with fluences in the range 0.1-1 J/cm 2 . The optical properties were studied by spectroscopicellipsometry (SE), while Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), and scanning electron microscopy (SEM) were performed for structure and surface morphology investigation.

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Synthesis and structural characterization and DFT calculations of the organic salt crystal obtaining 9-aminoacridine and picric acid: 9-Aminoacridinium picrate

“…Organic salt, 9-aminoacridinium picrate (9-AAcPc), containing equimolar quantities of 9aminoacridine and picric acid was obtained and a single crystal was grown by the slow evaporation method in the mixture of methanol: tetrahydrofuran solvent (1: 1, v: v). The molecular structure of the prepared compound was confirmed by FT-IR, 1 H NMR, and 13 C NMR spectroscopic methods, as well as single crystal X-ray diffraction analysis. The X-ray diffraction analysis of the crystal structure of the title compound showed the presence of the triclinic space group P-1 with no.…”