The densely populated North Sea region
encompasses catchments of rivers such as Scheldt and Meuse. Herein,
agricultural, industrial, and household chemicals are emitted, transported
by water, and deposited in sediments, posing ecological risks. Though
sediment monitoring is often costly and time-intensive, modeling its
toxicity to biota has received little attention. Due to high complexity
of interacting variables that induce overall toxicity, monitoring
data only sporadically validates current models. Via a range of concepts,
we related bio-physicochemical constituents of sediment in Flanders
to results from toxicity bioassays performed on the ostracod
Heterocypris incongruens
. Depending on the water
body, we explain up to 90% of the variance in
H. incongruens
growth. Though variable across Flanders’ main water bodies,
organotin cations and ammonia dominate the observed toxicity according
to toxic unit (TU) assessments. Approximately 10% relates to testing
conditions/setups, species variabilities, incoherently documented
pollutant concentrations, and/or bio-physicochemical sediment properties.
We elucidated the influence of organotin cations and ammonia relative
to other metal(oxides) and biocides. Surprisingly, the tributylin
cation appeared ∼1000 times more toxic to
H.
incongruens
as compared to “single-substance”
bioassays for similar species. We inferred indirect mixture effects
between organotin, ammonia, and phosphate. Via chemical speciation
calculations, we observed strong physicochemical and biological interactions
between phosphate and organotin cations. These interactions enhance
bioconcentration and explain the elevated toxicity of organotin cations.
Our study aids water managers and policy makers to interpret monitoring
data on a mechanistic basis. As sampled sediments differ, future modeling
requires more emphasis on characterizing and parametrizing the interactions
between bioassay constituents. We envision that this will aid in bridging
the gap between testing in the laboratory and field observations.