The interaction between blood pressure variability, obesity, and left ventricular mechanics

Tadić, Marijana; Cuspidi, Cesare; Penčić, Biljana; Andric, Anita; Pavlović, Smiljana; Iracek, Olinka; Ćelić, Vera

doi:10.1097/hjh.0000000000000830

Cited by 22 publications

(12 citation statements)

References 33 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Investigations showed that patients with prehypertension, white‐coat hypertension, and masked hypertension also had significantly reduced multidirectional LV strain in comparison with normotensive controls . All studies agreed that blood pressure level correlated well with LV multidirectional strain and the strongest correlation was found for LV longitudinal strain. It was demonstrated that LV strain correlated well with blood pressure level independently of LV hypertrophy, LV diastolic function, body mass index, and age.…”

mentioning

confidence: 70%

“…Investigations confirmed that LV mechanics, and primarily longitudinal strain, was impaired in AH patients . The spectrum of patients with AH in the published studies was wider each year, and effect of common comorbidities such as obesity, diabetes, and metabolic syndrome on LV strain was stronger in AH patients than in patients with isolated AH, diabetes, or obesity . This showed that these risk factors had more synergistic negative effect than simple additive effect.…”

mentioning

confidence: 76%

See 1 more Smart Citation

Left ventricular strain and arterial hypertension: Is longitudinal strain ready for primetime?

Tadić

Cuspidi

2020

J of Clinical Hypertension

Self Cite

View full text Add to dashboard Cite

More than one decade passed from the first studies regarding left ventricular (LV) mechanics in patients with arterial hypertension (AH). At the beginning, the assessment of LV strain was considered as a research tool, which was exclusively used in well-equipped echocardiographic laboratories. What is the situation nowadays and does LV strain still has status of "fancy gadget" or necessity in the evaluation of subclinical subtle cardiac damage in patients with AH?The first studies used tissue-Doppler derived LV strain and soon after speckle tracking imaging arrived and completely replaced tissue-Doppler strain technique. Pioneer investigations showed difference between physiological LV hypertrophy in athletes and pathological LV hypertrophy in AH patients using LV longitudinal strain. 1,2 However, studies that revealed LV strain deterioration in the young untreated hypertensive patients without LV hypertrophy broke the prejudice that LV hypertrophy is "conditio sine qua non" for LV strain reduction. 3The most of studies emphasized the effect of AH on LV longitudinal strain and impairment of LV circumferential and radial strains, if detected, was put aside. There are several reasons for this attitude of investigators. Namely, strain evaluation is unfortunately still vendor-dependent and this remains the most important limitation of this imaging technique for more than decade. A lot of effort was put in the attempt to establish similar kind of LV longitudinal strain calculation with different vendors, and nowadays, this difference is minimized, but still exists. 4 We are still far a way of establishing the same consensus in calculation of LV circumferential and radial strain. The other important reason that may explain focusing on LV longitudinal strain was the fact that most of vendors provided quick assessment only of LV longitudinal strain, whereas the evaluation of circumferential and radial strains required special software and therefore remained more scientific than clinical tool. The major problem was also setting proper cutoff values for all types of LV strain. This problem was almost overcome for LV longitudinal strain in the last couple of years, and current guidelines claimed that LV longitudinal strain should be >−20% in healthy persons. 5 However, the recommendation still considers −16% as the cutoff of normality. 5This only confirms uncertainty that still exists in this area and large gray zone of LV longitudinal strain (between −16% and −20%). We are not even close to make this kind of consensus for LV circumferential and radial strain. However, one thing is certain, when LV longitudinal strain assessment is made using the same vendor or software from the time of diagnosis through the whole follow-up, one could be certain that evaluation of strain is much more reproducible than calculation of LV ejection fraction over this period. 6 According to the physiological mechanics of LV systolic function, longitudinal dysfunction may serve as a marker at an early stage of myocardial damage, whereas the chang...

show abstract

mentioning

confidence: 70%

mentioning

confidence: 76%

Left ventricular strain and arterial hypertension: Is longitudinal strain ready for primetime?

Tadić

Cuspidi

2020

J of Clinical Hypertension

Self Cite

View full text Add to dashboard Cite

show abstract

“…BPV increases with bodyweight and possibly with insulin resistance. 20 Adult patients with arterial hypertension have higher systolic and diastolic BP, PP, and BPV. 21 Systolic BPV correlated with fasting glucose in children and adults.…”

Section: Blood Pressure Variabilitymentioning

confidence: 99%

Blood pressure regulation determined by ambulatory blood pressure profiles in children and adolescents with type 1 diabetes mellitus: Impact on diabetic complications

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Abdominal distribution of fat has a negative impact on blood pressure (BP), lipid metabolism, glucose tolerance or insulin resistance 3. Obesity correlates with left ventricular hypertrophy, and weight reduction is a factor restoring normal heart muscle mass 4. Cardiovascular risk is related to high BP, especially to isolated systolic hypertension as a cause of coronary heart disease and stroke 5 6.…”

Section: Introductionmentioning

confidence: 99%

What is the most important determinant of cardiometabolic risk in 60–65-year-old subjects: physical activity-related behaviours, overall energy expenditure or occupational status? A cross-sectional study in three populations with different employment status in Poland

et al. 2019

View full text Add to dashboard Cite

ObjectivesThe aim of the study was to determine whether cardiovascular risk factors may differ according to occupational status and whether physical activity related to total energy expenditure (PA-EE) and related to health-related behaviours (PA-HRB) is associated with common cardiovascular risk factors or metabolic syndrome in pre-elderly subjects.MethodsThree hundred subjects aged 60–65 were recruited and divided into three equal groups of white-collar, blue-collar workers and unemployed subjects; 50% were women. The subjects were tested for major cardiovascular risk factors such as smoking, anthropometric indices, blood pressure, lipid levels, glucose, uric acid and homocysteine. PA-EE and PA-HRB were assessed with PA questionnaires.ResultsBlue-collar workers displayed higher anthropometric indices, blood pressure and higher PA-EE in comparison with other two groups. PA-HRB had a positive impact on body mass indices, lipids, glucose, uric acid and the prevalence of metabolic syndrome, with no such relationship observed for PA-EE.ConclusionsThe greatest cardiovascular risk was observed in the blue-collar workers group. Only PA-HRB had a positive association with cardiometabolic risk profile. No relationship was observed for PA-EE. Thus, promoting everyday life and leisure time PA behaviours is crucial for preventing cardiometabolic risk in pre-elderly subjects, even in blue-collar workers with high work-related EE.

show abstract

The interaction between blood pressure variability, obesity, and left ventricular mechanics

Abstract: BP variability and LV deformation are significantly affected by obesity in untreated hypertensive patients. BP variability is associated with 2DE and 3DE LV mechanics independently of main clinical and echocardiographic characteristics.

Cited by 22 publications

References 33 publications

Left ventricular strain and arterial hypertension: Is longitudinal strain ready for primetime?

Left ventricular strain and arterial hypertension: Is longitudinal strain ready for primetime?

Blood pressure regulation determined by ambulatory blood pressure profiles in children and adolescents with type 1 diabetes mellitus: Impact on diabetic complications

What is the most important determinant of cardiometabolic risk in 60–65-year-old subjects: physical activity-related behaviours, overall energy expenditure or occupational status? A cross-sectional study in three populations with different employment status in Poland

Contact Info

Product

Resources

About