School-enterprise cooperation in talent cultivation enhances the quality of talent training, enriches and updates enterprise production resources, and promotes stable and healthy societal development. This paper, after reviewing relevant research materials, designs an evaluation index system for the university-enterprise cooperation talent training model for engineering majors in colleges and universities and employs the combination assignment method to calculate the weight value of each index. The comprehensive evaluation index method is used to assess the development level of the university-enterprise cooperation talent cultivation model. The cluster analysis is conducted for each college and university according to their measurement levels. The study results show that colleges and universities are classified into four types. Type A colleges and universities have the highest level of talent cultivation, though they only constitute 7.14% of the total. Type D colleges and universities are the least advanced in developing the school-enterprise cooperation talent cultivation model for engineering majors, with a score of 2.14 points. The correlation between the proportion of schools uniformly equipped with teachers’ terminals (0.493) and the development level of the university-enterprise cooperation talent cultivation model is the strongest. The optimization suggestions presented in this paper, in response to the research findings, provide an innovative and breakthrough direction for the university-enterprise cooperation talent cultivation model in colleges and universities.