The Interactions of Midazolam and Flumazenil on Human Memory and Cognition

Children's Memories for Painful Cancer Treatment Procedures: Implications for Distress

“…These findings also may explain anecdotal evidence that children on Versed often continue to display anticipatory anxiety before each LP. A number of experimental studies have found that Versed impairs memory (Ghoneim, Block, Ping, El-Zahaby, & Hinrichs, 1993;Kupietzky, Holan, & Shapira, 1996); however, one significant difference between these studies and the present one is that memory in previous studies typically was tested through recall of word lists. Although participants have a more difficult time concentrating on tasks such as remembering word lists when given Versed, they may be able to focus on and remember events that are personally relevant.…”

A double-blind, placebo-controlled single dose trial of intravenous flumazenil in Alzheimer's disease

“…A baseline CDR battery was performed before an intravenous injection of either¯umazenil 1 mg or normal saline (both 10 ml volumes) over 10 min. This dose was chosen as it has been shown to be sucient to completely reverse memory eects of benzodiazepines in healthy volunteers (Ghoneim et al, 1993). Cognitive testing was then repeated at 5, 30 and 240 min following injection.…”

Combining alprazolam with systematic desensitization therapy for dental injection phobia

“…The assessment was an explicit memory task that asked subjects to recall an arbitrary list of words (Ghoneim, Block, Ping, el-Zahaby, & Hinrichs, 1993). A new list was used each session.…”