The interactive effects of selenomethionine and methylmercury on their absorption, disposition, and elimination in juvenile white sturgeon

Huang, Shengshu; Strathe, A. B.; Fadel, James G.; Johnson, Michael L.; Lin, Pei; Liu, Tsung‐Yun; Hung, Silas S.O.

doi:10.1016/j.aquatox.2012.09.018

Cited by 24 publications

(13 citation statements)

References 46 publications

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“…Similar results were found in Sacramento splittail larvae (Deng et al 2008) and other fish and mammals (Chen, Belzile & Gunn 2001;Belzile, Chen, Gunn, Tong, Alarie & Delonchamp 2006;Huang et al 2013). Fish fed the diets in combination with vitamin E and Se or higher levels of vitamin E-contained diet alone (200 mg TA kg À1 ) had significantly reduced mercury content in muscle than those of the fish fed only Se-fortified diets (2 or 4 mg SeMet kg À1 ) and lower levels of vitamin E-contained diet (100 mg TA kg À1 ).…”

Section: Discussionsupporting

confidence: 72%

“…Other studies suggest that whole body concentrations of 10-20 mg kg À1 Hg could be lethal to fish (Niimi & Kissoon 1994). According to Huang, Strathe, Fadel, Johnson, Lin, Liu and Hung (2013), Se had protective effects on Hg toxicity when administered together in the diet. However, fish fed 4 mg SeMet kg À1 showed growth improvement in the absence of vitamin E. Penglase et al (2014b) reported elevated dietary SeMet (10 ppm) could partially protect adult female zebrafish, Danio rerio, from MeHg-induced reduction in growth and survival.…”

Section: Discussionmentioning

confidence: 99%

“…It was reported that the presence of Se and vitamin E might allow for sustained decomposition of MeHg (Ganther 1980). Interaction between Se and Hg varies among species and/or experimental conditions, particularly between exposure method and duration of the exposure (Huang et al 2013). Selenomethionine is approximately three times more bioavailable to fish than inorganic Se as sodium selenite (NRC 2011).…”

Section: Discussionmentioning

confidence: 99%

“…In contrast, the same group of researchers postulated that SeMet and MeHg had a synergistic negative effect on zebrafish reproduction (Penglase et al 2014b). According to Huang, Strathe, Fadel, Johnson, Lin, Liu and Hung (2013), Se had protective effects on Hg toxicity when administered together in the diet. Selenium reduces Hg availability, either by forming biologically inert complexes and/or associating with selenoproteins.…”

Section: Discussionmentioning

confidence: 99%

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Synergistic effects of dietary vitamin E and selenomethionine on growth performance and tissue methylmercury accumulation on mercury-induced toxicity in juvenile olive flounder, Paralichthys olivaceus (Temminck et Schlegel)

et al. 2015

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An 8-week feeding trial was conducted to evaluate the synergistic effects of dietary vitamin E and selenomethionine (SeMet) on induced methylmercury (MeHg) toxicity in juvenile olive flounder Paralichthys olivaceus. Nine semi-purified diets were formulated to contain three different vitamin E levels as DL-a-tocopheryl acetate (0, 100 and 200 mg TAkg À1 diet) and three different selenium (Se) levels (0, 2 and 4 SeMet mg kg À1 diet) on the constant mercury toxicity level (20 mg MeHgkg À1 diet). Nine experimental diets, 4 ), were fed to triplicate groups of fish averaging 2.3 AE 0.04 g (mean AE SD) in the semi-recirculation system. After 8 weeks of feeding trial, vitamin E and Se showed significant effects on weight gain (WG) of fish (P < 0.05). We found that there was a clear trend of increasing WG with elevating vitamin E and Se levels in the diets. Feed efficiency (FE), specific growth rate (SGR), protein efficiency ratio (PER) and survivability exhibited a similar trend with WG. Both antioxidants had significant interaction effects on FE and PER (P < 0.05). Methylmercury concentrations in fish muscle, liver and kidney decreases in a dose-dependent manner as dietary vitamin E and Se levels increase. Interestingly, the most significant interactive effects of vitamin E and Se were found in liver tissue for depleting Hg concentrations (P < 0.05). These findings suggest that dietary vitamin E more than 100 mg TA kg À1 diet with 2 or 4 mg SeMet kg À1 -supplemented diets could have synergistic effects on growth and liver mercury bioaccumulation on MeHg-induced toxicity in juvenile olive flounder.

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Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Synergistic effects of dietary vitamin E and selenomethionine on growth performance and tissue methylmercury accumulation on mercury-induced toxicity in juvenile olive flounder, Paralichthys olivaceus (Temminck et Schlegel)

et al. 2015

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“…Deng et al (2000) had developed a combined technique that introduces oesophageal intubation, dorsal aorta cannulation and urinary catheterization into sturgeon study (Deng et al, 2000). This newly developed method had been successfully applied in white sturgeon (Acipenser transmontanus) to study the utilization of different sources and dosage of carbohydrates, the metabolic kinetics of methylmercury and selenium (Deng, Refstie, & Hung, 2001;Gisbert, Sainz, & Hung, 2003;Huang et al, 2013;Huang, Strathe, Fadel, et al, 2012a;Huang, Strathe, Hung, Boston, & Fadel, 2012;Huang, Strathe, Hung, et al, 2012;Tashjian, Teh, Sogomonyan, & Hung, 2006). The technique has the advantages of allowing quantitative delivery of nutrients, repeat sampling of blood and continuous collection of urine from individual fish with minimum stress, which would be making nutritional study in sturgeon more precise, efficient and economical than traditional growth study (Deng et al, 2000;Mazik, Plakas, & Stehly, 1994;Tashjian & Hung, 2003).…”

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confidence: 99%

Responses of hybrid sturgeon ( Huso dauricus ♀ × Acipenser schrenckii ♂ ) to oral administration of phosphorus

et al. 2020

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To better understand the phosphorus (P) utilization in hybrid sturgeon (Huso dauricus ♀ × Acipenser schrenckii ♂), a combined technique with oesophageal intubation, dorsal aorta cannulation and urinary catheterization was used in the present study. Groups of five hybrid sturgeon were orally administrated with graded doses of P (0, 50, 100 and 200 mg P/kg BW) in the form of monocalcium phosphate. The high dose of P (200 mg P/kg BW) caused a significant increase in plasma P concentration. Plasma calcium (Ca) concentrations were significantly increased in the fish treated with 0 and 100 mg P/kg BW. Both P and urea excretion showed increased changing pattern with increasing P intubation level and exhibited significant higher value in 200 mg P/kg BW group. A significant increase in Ca excretion was found in the group without P supplementation (0 mg P/kg BW). ALP and SOD activity in plasma was inhibited in fish at P‐deficient groups (0 and 50 mg P/kg BW). The data in the current study showed that hybrid sturgeon at 100 mg P/kg BW treatment exhibited better P and Ca utilizations with lower waste excretion, as well as favourable status of anti‐oxidation.

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Organ-specific accumulation, transportation, and elimination of methylmercury and inorganic mercury in a low Hg accumulating fish

Peng

Liu

Wang

2016

Environmental Toxicology and Chemistry

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Low mercury (Hg) concentrations down to several nanograms Hg per gram of wet tissue are documented in certain fish species such as herbivorous fish, and the underlying mechanisms remain speculative. In the present study, bioaccumulation and depuration patterns of inorganic Hg(II) and methylmercury (MeHg) in a herbivorous rabbitfish Siganus canaliculatus were investigated at organ and subcellular levels following waterborne or dietary exposures. The results showed that the efflux rate constants of Hg(II) and MeHg were 0.104 d(-1) and 0.024 d(-1) , respectively, and are probably the highest rate constants recorded in fish thus far. The dietary MeHg assimilation efficiency (68%) was much lower than those in other fish species (∼90%). The predominant distribution of MeHg in fish muscle was attributable to negligible elimination of MeHg from muscle (< 0) and efficient elimination of MeHg from gills (0.12 d(-1) ), liver (0.17 d(-1) ), and intestine (0.20 d(-1) ), as well as efficient transportation of MeHg from other organs into muscle. In contrast, Hg(II) was much more slowly distributed into muscle but was efficiently eliminated by the intestine (0.13 d(-1) ). Subcellular distribution indicated that some specific membrane proteins in muscle were the primary binding pools for MeHg, and both metallothionein-like proteins and Hg-rich granules were the important components in eliminating both MeHg and Hg(II). Overall, the present study's results suggest that the low tissue Hg concentration in the rabbitfish was partly explained by its unique biokinetics. Environ Toxicol Chem 2016;35:2074-2083. © 2016 SETAC.

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The interactive effects of selenomethionine and methylmercury on their absorption, disposition, and elimination in juvenile white sturgeon

Cited by 24 publications

References 46 publications

Synergistic effects of dietary vitamin E and selenomethionine on growth performance and tissue methylmercury accumulation on mercury-induced toxicity in juvenile olive flounder, Paralichthys olivaceus (Temminck et Schlegel)

Synergistic effects of dietary vitamin E and selenomethionine on growth performance and tissue methylmercury accumulation on mercury-induced toxicity in juvenile olive flounder, Paralichthys olivaceus (Temminck et Schlegel)

Responses of hybrid sturgeon ( Huso dauricus ♀ × Acipenser schrenckii ♂ ) to oral administration of phosphorus

Organ-specific accumulation, transportation, and elimination of methylmercury and inorganic mercury in a low Hg accumulating fish

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