The International Burden of Migraine Study (IBMS): Study design, methodology, and baseline cohort characteristics

Payne, Krista A.; Varon, Sepideh F.; Kawata, Ariane K.; Yeomans, Karen; Wilcox, Teresa K.; Manack, Aubrey; Buse, Dawn C.; Lipton, Richard B.; Goadsby, PJ; Blumenfeld, Andrew

doi:10.1177/0333102411410610

Cited by 59 publications

(80 citation statements)

References 42 publications

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“…As in prior studies, we found a female preponderance both for CM and EM 4 8 16. The CM group was slightly older, reported lower household income, was less likely to be employed, reported a greater number of comorbid conditions and had higher MIDAS scores, signifying more severe headache-related disability.…”

Section: Discussionsupporting

confidence: 79%

Headache-related health resource utilisation in chronic and episodic migraine across six countries

Sanderson

Devine

Lipton

et al. 2013

J Neurol Neurosurg Psychiatry

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ObjectiveTo describe headache-related health resource usage in chronic and episodic migraine across six countries.MethodsA web-based questionnaire eliciting data on several topics, including health resource usage, was administered to panellists with migraine from the USA, Canada, UK, Germany, France and Australia. Respondents were grouped into episodic and chronic migraine, based on reported headache phenotype and headache-day frequency. ORs were calculated, comparing usage in each country to that in the US, controlling for chronic versus episodic migraine and other factors.ResultsRelative to the USA, the odds of visiting a provider for headache during the preceding 3 months were significantly higher in all countries, except Germany. Respondents in France were more likely to report having a provider they typically visited for headache-related care. The odds of visiting the emergency department for headache were significantly lower in France, the UK and Germany, and hospitalisation for headache was significantly more frequent in Canada and Australia. Respondents from all countries, except Canada, were more likely to report currently using a prescription-acute treatment, and those from France were more likely to report trying more than three acute treatments. Preventive treatment use did not differ significantly.ConclusionsHeadache-related resource usage differed significantly between the USA and other countries. US respondents were generally less likely to report recent provider visits and use of prescription-acute treatments. They were more likely to report emergency department visits than in European countries, but less likely to report hospitalisation than in Canada and Australia.

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Section: Discussionsupporting

confidence: 79%

Headache-related health resource utilisation in chronic and episodic migraine across six countries

Sanderson

Devine

Lipton

et al. 2013

J Neurol Neurosurg Psychiatry

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“…IBMS was a cross-sectional, Web-based observational survey of participants from the United States, Australia, Canada, Germany, United Kingdom, France, Spain, Italy, Taiwan, and Brazil. Detailed methods and primary results of the IBMS have been published elsewhere [17,23]. The data used in this analysis include information from Brazil.…”

Section: Source Of Datamentioning

confidence: 99%

“…Annual direct cost estimates for those with migraine have ranged from $100 to more than $7000 per person per year [17]. These unpredictable attacks involve pulsating unilateral head pain of moderate-to-severe intensity accompanied by nausea, vomiting, and sensitivity to light and noise [18].…”

Section: Introductionmentioning

confidence: 99%

Mapping from Disease-Specific Measures to Health-State Utility Values in Individuals with Migraine

et al. 2012

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“…Within the US migraine population, the majority (93.3%) are classified as having EM, but those who have CM (7.7%)4 are recognized as the segment suffering most from the disorder. Supported by clinical experience, data have demonstrated that compared with people with EM, those with CM experience substantially greater headache impact on daily activities,5, 6 higher direct medical costs,7, 8, 9 greater healthcare resource utilization,5 reduced health‐related quality of life,5, 10 and higher rates of comorbidities 11, 12…”

Section: Introductionmentioning

confidence: 99%

Assessing Barriers to Chronic Migraine Consultation, Diagnosis, and Treatment: Results From the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study

et al. 2016

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ObjectiveTo assess the rates and predictors of traversing steps essential to good medical care for chronic migraine, including: (1) medical consultation, (2) accurate diagnosis, and (3) minimal pharmacologic treatment. Candidate predictors included socioeconomic, demographic, and headache‐specific variables.BackgroundPrevious research has established that barriers to effective management for episodic migraine include the absence of health insurance, lack of appropriate medical consultation, failure to receive an accurate diagnosis, and not being offered a regimen with acute and preventive treatments.Methods/DesignThe Chronic Migraine Epidemiology and Outcomes (CaMEO) Study, a longitudinal web‐based panel study of migraine, included a cross‐sectional module focused on patterns of and barriers to medical care. Participants eligible for this analysis met the study criteria for chronic migraine, had evidence of headache‐related disability, and provided data on health insurance status. The main outcomes in the current analysis included the proportion of respondents who sought consultation for headache with a designated healthcare professional, self‐reported receiving a diagnosis of chronic or transformed migraine, and received minimal pharmacologic treatment for headache with a focus on prescribed acute and preventive treatments.ResultsIn the CaMEO Study, 80,783 respondents provided study data, 16,789 (20.8% of respondents) met criteria for migraine, and 1476 (8.8% of those with migraine) met chronic migraine criteria. In total, 1254 participants (85.0% of those with chronic migraine) met inclusion criteria for this analysis. Of those, 512 respondents (40.8%) reported currently consulting with a healthcare professional for headache. Odds of consulting increased with increasing age (OR 1.02; 95% CI 1.01–1.03), body mass index (BMI) (OR 1.01; 95% CI 1.00–1.03), migraine‐related disability (OR 1.02; 95% CI 1.00–1.04), and migraine severity (OR 1.16; 95% CI 1.11–1.22) and presence of health insurance (OR 4.61; 95% CI 3.05–6.96). Among those consulting a healthcare professional, 126 (24.6%) received an accurate diagnosis and 56 of those with a correct diagnosis (44.4%) received both acute and preventive pharmacologic treatments; odds of a CM diagnosis were higher for women (OR 1.93; 95% CI 1.03–3.61), those with greater migraine severity (OR 1.25; 95% CI 1.14–1.37), and those currently consulting a specialist (OR 2.38; 95% CI 1.54–3.69). No predictors of receiving appropriate treatment were identified among those currently consulting. Among our sample of people with chronic migraine, only 56 (4.5%) individuals successfully traversed the series of 3 barriers to successful chronic migraine care (ie, consulted a healthcare professional for migraine, received an accurate diagnosis, and were prescribed minimal acute and preventive pharmacologic treatments).ConclusionOur findings suggest that <5% of persons with chronic migraine traversed 3 barriers to receiving care for headache (consultation, diagnosis, and treatment), represe...

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The International Burden of Migraine Study (IBMS): Study design, methodology, and baseline cohort characteristics

Abstract: This is the first large international cohort of persons with chronic and episodic migraine studied using a web-based approach, a methodology well suited to the study of the burden of migraines.

Cited by 59 publications

References 42 publications

Headache-related health resource utilisation in chronic and episodic migraine across six countries

Headache-related health resource utilisation in chronic and episodic migraine across six countries

Mapping from Disease-Specific Measures to Health-State Utility Values in Individuals with Migraine

Assessing Barriers to Chronic Migraine Consultation, Diagnosis, and Treatment: Results From the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study

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