The intestinal microbiota reconfigures the boundaries of knowledge

Popa, Gabriela-Loredana; Gheorghe, Silvana-Adelina; Preda, Mădălina; Popa, Mircea Ioan

doi:10.26416/inf.49.1.2017.678

Cited by 3 publications

(4 citation statements)

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“…The intestinal microbiota is a vital part of the body, playing numerous roles, from the synthesis of compounds to actions in the metabolism of endo- and exogenous substances [ 176 ]. Bacterial diversity of the microbiota can influence the proper functioning of the body and the appearance of pathologies [ 177 ].…”

Section: Antibiotics and Microbiotamentioning

confidence: 99%

Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening

et al. 2021

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Antibiotics are considered as a cornerstone of modern medicine and their discovery offers the resolution to the infectious diseases problem. However, the excessive use of antibiotics worldwide has generated a critical public health issue and the bacterial resistance correlated with antibiotics inefficiency is still unsolved. Finding novel therapeutic approaches to overcome bacterial resistance is imperative, and natural compounds with antibacterial effects could be considered a promising option. The role played by antibiotics in tumorigenesis and their interrelation with the microbiota are still debatable and are far from being elucidated. Thus, the present manuscript offers a global perspective on antibiotics in terms of evolution from a historical perspective with an emphasis on the main classes of antibiotics and their adverse effects. It also highlights the connection between antibiotics and microbiota, focusing on the dual role played by antibiotics in tumorigenesis. In addition, using the natural compounds with antibacterial properties as potential alternatives for the classical antibiotic therapy is discussed.

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Section: Antibiotics and Microbiotamentioning

confidence: 99%

Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening

et al. 2021

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“…The exact composition of the microbiota is specific to each individual and changes throughout life, being influenced by environmental factors: diet, lifestyle, stress, medication (especially oral antibiotics), and some invasive procedures (e.g., colonoscopy) [10].…”

Section: Discussionmentioning

confidence: 99%

“…For example, the presence of lactobacilli generates the expression of opioid and cannabinoid receptors on the surface of epithelial cells [9]. Microbiota also influences the physiology of the gut by local production of gases: CO 2 , H 2 , methane, and hydrogen sulphide, recently classified as a gasotransmitter, due to its effect in modulating inflammation in the gut [10].…”

Section: The Gut-brain Axismentioning

confidence: 99%

Gut–Brain Axis, Microbiota and Probiotics—Current Knowledge on Their Role in Irritable Bowel Syndrome: A Review

Marginean,

Popescu,

Drocas

et al. 2023

Gastrointestinal Disorders

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Irritable bowel syndrome (IBS) is a common digestive disorder with a significant impact on both individuals and society in terms of quality of life and healthcare costs. A growing body of research has identified various communication pathways between the microbiota and the brain in relation to motility disorders, with the gut–brain axis being key to the pathogenesis of IBS. Multiple factors contribute to the pathogenetic pathways in IBS, including immune mechanisms, psychosocial factors, increased oxidative stress and pro-inflammatory cytokine release, as well as genetic and hormonal factors. Increased permeability of the normal intestinal barrier allows bacterial products to access the lamina propria, providing a mechanism for perpetuating chronic inflammation and characteristic symptoms. The microbiota influences inflammatory processes in IBS by altering the balance between pro-inflammatory factors and host defence. Probiotics modulate the pathophysiological mechanisms involved in IBS by influencing the composition of the microbiota and improving intestinal motility disorders, visceral hypersensitivity, immune function of the intestinal epithelium, metabolic processes in the intestinal lumen, dysfunction of the microbiota-GBA, and are recognised as effective and safe in IBS therapy. Our study aimed to provide a comprehensive overview of the relationship between the gut–brain axis, microbiota, and IBS, based on current information.

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“…Fundamentalcharacteristicsofinnovationarethosethatdon'tchangestartingwithonebanking frameworkthenontothenextandarefirmlyassociatedwiththebankingsettinginwhichinnovation happens (Popa et al, 2010). Different researchers (Damanpour, 1991) have recognized different highlightsofinnovation,forexample,theextentanditsimpactsonfirms'proficiency,lookingto breakdownthecontrastsamongsteadyandradicalinnovation.…”

Section: Review Of Literaturementioning

confidence: 99%

Innovation, M-Banking, and Customer Satisfaction

Moudud‐Ul‐Huq

2021

International Journal of Corporate Finance and Accounting

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Innovation through information technology (IT) has made advances all over, and banking is no exemption to it. The utilization of technology has gotten pervasive in the present banking institutions. Mobile banking is a recently included service in the banking area that facilitates banking by means of mobile gadgets. Mobile banking has stamped itself as a rising technology embraced by banks the world over. That's why this investigation is to recognize the effect of innovation, mobile banking on customer satisfaction and decide the elements that lead to customer satisfaction. By reviewing literature, the authors propose a model and to demonstrate the model accuracy dependent on information gathered from 269 respondents utilizing on the web media. To examine the aforesaid relationships, they use the partial least squares (PLS)-structural equation modeling (SEM) technique. The aftermath of their investigation uncovers that there is a noteworthy connection between innovation (I) and mobile banking (MB) on customer satisfaction. Then again, innovation has positive effect on mobile banking.

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The intestinal microbiota reconfigures the boundaries of knowledge

Cited by 3 publications

References 0 publications

Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening

Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening

Gut–Brain Axis, Microbiota and Probiotics—Current Knowledge on Their Role in Irritable Bowel Syndrome: A Review

Innovation, M-Banking, and Customer Satisfaction

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