The Intimate Relationship between Vestibular Migraine and Meniere Disease: A Review of Pathogenesis and Presentation

Liu, Yuan F.; Xu, Helen

doi:10.1155/2016/3182735

Cited by 55 publications

(52 citation statements)

References 81 publications

(140 reference statements)

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“…It could be speculated that both findings, those concerning accompanying symptoms and family history, may underline some possible overlapping pathophysiological mechanism between MD and VM; it is known for example that MD subjects present a higher rate of migraine than the total population . Conversely, in the early stages of both disorders, differential diagnosis may be a troublesome issue in some cases …”

Section: Discussionmentioning

confidence: 99%

“…25 Conversely, in the early stages of both disorders, differential diagnosis may be a troublesome issue in some cases. [26][27][28] Finally, interesting considerations may be drawn from the data on migraine precursors. In our cohort, we found that 69% of patients referred at least one of the pediatric precursors of migraine; in particular, 42.8% of subjects referred motion sickness.…”

Section: Discussionmentioning

confidence: 99%

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Clinical Features, Familial History, and Migraine Precursors in Patients With Definite Vestibular Migraine: The VM‐Phenotypes Projects

et al. 2017

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Clinical Features, Familial History, and Migraine Precursors in Patients With Definite Vestibular Migraine: The VM‐Phenotypes Projects

et al. 2017

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“…First of all, many studies have highlighted the overlap between vestibular and migraine pathways, as the caudal parabrachial nucleus receives both afferent peripheral trigeminal nociceptive and vestibular input, and also the trigeminal nerve affects the inner ear by cochlear vasculature innervations [31]. So, the cause of VM may be direct central activation of vestibular centres by the trigeminovascular system together with its effects on the inner ear [32]. It seems that vestibular symptoms come from the vestibular nuclei, which are simultaneously suppressed by inhibitory feedback from the cerebellar nodulus and uvula [33].…”

Section: Pathophysiology Of Vmmentioning

confidence: 99%

“…Regardless of the many differences between these disorders, one should remember that, at very early stages, most symptoms can be quite similar. Meniere's Disease is a disorder with attacks of coexisting vertigo, tinnitus, aural fullness, and hearing loss [32]. MD is known to be associated with migraine, as the lifetime prevalence of migraine is higher in the MD group compared to controls, and almost half of MD patients may experience headache, photophobia or aura during Meniere's attacks [32,52].…”

Section: Differential Diagnosismentioning

confidence: 99%

Vestibular migraine — an underdiagnosed cause of vertigo. Diagnosis and treatment

Nowaczewska

2020

Neurol Neurochir Pol.

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Introduction. Migraine and vertigo are two common conditions. The main disorder connecting both these entities is vestibular migraine (VM). State of the art. VM may affect 1-3% of the general population. It is a disabling disease of recurrent attacks of vestibular symptoms accompanied by migraine features which occur in patients with a current or previous history of migraine. The episodes can last minutes, hours or even days, and may occur without any concurrent headache, which can prompt misdiagnosis. VM often begins several years after a typical migraine, and the delay between onset of headache and vertigo may be long. The diagnosis is based on the patient's clinical history and can be challenging due to the lack of an established confirmatory diagnostic test or biomarkers. The mechanism of vestibular migraine remains unclear and is still under investigation, but it seems to be an interaction between trigeminal and vestibular systems. Due to the lack of specific trials, treatment recommendations are based on migraine guidelines. Several drugs seem to be effective, although there have been few randomised controlled trials in this area. Regardless of the published strict and detailed diagnostic criteria, this condition remains little known, and as a consequence is underdiagnosed and undertreated. Clinical implications. Efforts should be made to educate medical communities and patients about this disease and to encourage neurologists and ENT specialists to cooperate. Every patient with vertigo of unknown origin should be directly asked about a past or present history of migraine, or migraine symptoms experienced during their vertigo episodes. Future directions. There is a growing need for studies regarding the pathophysiology of VM as well as randomised trials to establish clear treatment recommendations and to improve management of this surprisingly common disorder.

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“…15 MD has also been related to migraine in several studies, and a possible common etiology has been suggested. 16,17 This review focuses on the current knowledge and clinical management in MD. For this purpose, we have conducted a systematic review of the literature, including MD studies published in the past 5 years.…”

mentioning

confidence: 99%

Current Understanding and Clinical Management of Meniere's Disease: A Systematic Review

Pérez-Carpena

Lopez-Escamez

2019

Semin Neurol

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Meniere's disease (MD) is a set of uncommon disorders with core phenotype of tinnitus, episodic vertigo, and sensorineural hearing loss. MD shows a genetic predisposition and a family history is found in 10% cases, with an autosomal dominant inheritance pattern. It is a multifactorial condition whose onset and development are triggered by the combined effect of genetic and environmental factors. Histopathological studies have associated MD with the accumulation of endolymph in the cochlea and the vestibular organs. However, endolymphatic hydrops does not fully explain the persistence of tinnitus, hearing loss progression, or the frequency of vertigo attacks.There are several comorbidities associated with MD, such as migraine, anxiety, autoimmune, and autoinflammatory disorders, adding more complexity to the phenotype. This “extended phenotype” can make the diagnosis and clinical management more complex, but it could also lead to a better characterization, understanding, and treatment of MD patients.We have conducted a systematic review on MD to update current knowledge, focusing on its mechanisms, diagnosis, comorbidities, and practical management.

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The Intimate Relationship between Vestibular Migraine and Meniere Disease: A Review of Pathogenesis and Presentation

Cited by 55 publications

References 81 publications

Clinical Features, Familial History, and Migraine Precursors in Patients With Definite Vestibular Migraine: The VM‐Phenotypes Projects

Clinical Features, Familial History, and Migraine Precursors in Patients With Definite Vestibular Migraine: The VM‐Phenotypes Projects

Vestibular migraine — an underdiagnosed cause of vertigo. Diagnosis and treatment

Current Understanding and Clinical Management of Meniere's Disease: A Systematic Review

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