The introduction of the disconnection approach into polymer synthesis

Abstract

The disconnection approach, a widely utilized method of design synthesis route, has played crucial roles in contemporary organic chemistry for decades. Here, we provide an introduction to the construction of polymer main chains. The implementation of the strategy hinges on determining where to disconnect based on the successful polymerization reaction in order to infer a suitable monomer. By investigating specific covalent bonds and structures in polymers, several specific linkers are highlighted to demonstrate how to design and synthesize polymer main chains using reverse thinking, thus inspiring those in polymer synthesis.