“…These results on second-order MDEs, together with the so-called completely continuous dependence of eigenvalues on measures, have been extended in [16] to some class of third-order symmetric MDEs. Motivated by the study on the Camassa-Holm equation [8,9] and general strings, some spectral and inverse spectral problems on second-order GODEs with indefinite distributions as weights have been developed in [11,12,13] and are still under developing. In order to solve problems (4) and ( 5) and for the theoretical purpose, in this paper, by taking indefinite measures ρ ∈ M 0 (I), we will give a relatively complete study on the (positive) principal eigenvalues of MDEs ( 8 As before, by a principal eigenvalue λ of ( 8)-(N ), we always refer λ to a positive principal eigenvalue.…”