The Investigation and Differential Diagnosis of Dementias

Mahlberg, Richard

doi:10.3238/arztebl.2010.0675

Cited by 2 publications

(1 citation statement)

References 2 publications

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“…We therefore used a combination of the short MMSE and the Global Deterioration Score for an estimation. This score identified participants suffering from poor cognitive functioning and related limitations, but cannot replace a diagnosis (23). Thus, this finding has to be interpreted with caution.…”

Section: Discussionmentioning

confidence: 88%

Health and Disease at Age 100: Findings From the Second Heidelberg Centenarian Study

Jopp¹,

Boerner²,

Rott³

2016

Deutsches Ärzteblatt International

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German centenarians experienced a substantial number of ill nesses, dominated by sensory and mobility conditions. Cardiovascular diseases were the only potentially lethal illnesses with high prevalence. Evidence of unaddressed pain seems alarming, requiring future research. Emerging health profiles indicate that even in very advanced age, quality of life may be improved by enhanced diagnostics and optimal disease management. Mobility limitations may be addressed with preventive efforts.

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Section: Discussionmentioning

confidence: 88%

Health and Disease at Age 100: Findings From the Second Heidelberg Centenarian Study

Jopp¹,

Boerner²,

Rott³

2016

Deutsches Ärzteblatt International

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Frequency of dementia syndromes with a potentially treatable cause in geriatric in-patients: analysis of a 1-year interval

Djukic

Wedekind²,

Franz

et al. 2015

Eur Arch Psychiatry Clin Neurosci

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In addition to neurodegenerative and vascular causes of dementia, in the differential diagnosis potentially reversible conditions of dementia also must be assessed. Routine laboratory parameters and neuroimaging, which are recommended for the differential diagnosis of suspected dementia by the German S3 Guideline "Dementia", were retrospectively studied in 166 geriatric patients with suspected dementia. Delirium was diagnosed in six patients (3.6%). These six patients were excluded from the study. Of the 160 remaining patients, there were 99 (59.6%) with an already known dementia. In this subgroup of patients, we found a potentially treatable cause of dementia in 18.2%. In the remaining 61 patients (36.8%), the newly diagnosed dementia syndrome was established according to ICD-10 criteria. Potentially reversible causes of the dementia syndrome were found in 19 of these patients (31.1%). The most common cause was depressive pseudodementia in eight patients followed by vitamin B12 deficiency in six patients. A significant amount of our patients showed laboratory or imaging changes suggestive of potentially reversible causes of the dementia syndrome upon admission. The results of our study indicate the importance of careful differential diagnosis of dementia based on the recommendations of guidelines. Although therapy of these potential causes is not always accompanied by a full recovery, the identification and therapy of treatable causes of cognitive deficits are possible even for general practitioners, who often are the primary contact persons of affected individuals.

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The Investigation and Differential Diagnosis of Dementias

Cited by 2 publications

References 2 publications

Health and Disease at Age 100: Findings From the Second Heidelberg Centenarian Study

Health and Disease at Age 100: Findings From the Second Heidelberg Centenarian Study

Frequency of dementia syndromes with a potentially treatable cause in geriatric in-patients: analysis of a 1-year interval

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