The investigation of biocompatibility and apical microleakage of tricalcium phosphate based root canal sealers

Bilginer, Suzan; Esener, I Timur; Söylemezoğlu, Figen; Tiftik, Ali Muhtar

doi:10.1016/s0099-2399(97)80255-5

Cited by 26 publications

(21 citation statements)

References 14 publications

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“…Its powder component comprises alpha-tricalcium phosphate and hydroxyapatite, and its liquid component contains polyacrylic acid which exhibits some degree of cytotoxicity 13) . Its sealing ability was comparable to Grossman sealer 14) but lower than that of AH Plus 15) . 16) .…”

Section: Introductionmentioning

confidence: 85%

Interfacial adaptation and thickness of bioceramic-based root canal sealers

Al‐Haddad

Kasim

Aziz

2015

Dental Materials Journal

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This study evaluated and compared the sealer thickness and interfacial adaptation of bioceramic sealers (Sankin Apatite III, MTA Fillapex ® , EndoSequence ® BC) to root dentin against AH Plus ® sealer. Sixty extracted single-root premolars were prepared and equally divided into four groups. Sealers were labeled with 0.1% Rhodamine B fluorescent dye. Roots were dissected along the transverse plane at 1 mm (apical), 3 mm (middle), and 6 mm (coronal) levels. Sealer-to-whole canal area ratio was evaluated. Percentage of gap-containing region to canal circumference was calculated using a confocal laser microscope. Sealer thickness was significantly higher at apical and middle levels than at coronal level. EndoSequence BC had the significantly highest thickness compared with MTA Fillapex and AH Plus. The coronal level had significantly less interfacial gaps compared with apical and middle levels. Bioceramic sealers showed more gaps compared with AH Plus, with no significant differences among them.

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Section: Introductionmentioning

confidence: 85%

Interfacial adaptation and thickness of bioceramic-based root canal sealers

Al‐Haddad

Kasim

Aziz

2015

Dental Materials Journal

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“…Although in vitro assays may not correlate highly with in vivo data, there were two histopathological studies on these materials that seem to contradict each other 9,10) . Bilginer et al 9) reported a mild to moderate inflammatory reaction to ARS, and suggested that ARS Type II and III were found more biocompatible than ARS Type I.…”

Section: ⅳ Discussionmentioning

confidence: 99%

“…Bilginer et al 9) reported a mild to moderate inflammatory reaction to ARS, and suggested that ARS Type II and III were found more biocompatible than ARS Type I. Whereas Yoshikawa et al 10) reported a severe inflammatory reaction to ARS Type I.…”

Section: ⅳ Discussionmentioning

confidence: 99%

“…Biocompatibility studies on ARS have been conducted by several researchers [9][10][11] . Efforts for histopathological evaluation on these materials seem to contradict each other 9,10) .…”

Section: ⅰ Introductionmentioning

confidence: 99%

“…Biocompatibility studies on ARS have been conducted by several researchers [9][10][11] . Efforts for histopathological evaluation on these materials seem to contradict each other 9,10) . Bilginer et al 9) reported a mild to moderate inflammatory reaction to ARS, whereas Yoshikawa et al 10) reported a severe inflammatory reaction.…”

Section: ⅰ Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of the cytotoxicity of calcium phosphate root canal sealers

Lee

Baek

Bae

2003

J Korean Acad Conserv Dent

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Cytotoxicity, calcium release, and pH changes generated by novel calcium phosphate cement formulations

et al. 2010

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Few published studies describe the biological properties of calcium phosphate cements (CPCs) for dental applications. We measured several biologically relevant properties of 3 CPCs over an extended (8 wk) interval. Monocalcium phosphate, calcium oxide, and synthetic hydroxyapatite were combined with either modified polyacrylic acid, light-activated modified polyalkenoic acid, or 35% w/w polymethyl vinyl ether maleic acid to obtain Types I, II, and III CPCs, respectively. Set cements were placed in direct contact with L929 fibroblasts for up to 8 weeks. Media Ca(+2) and pH were determined by atomic absorption spectroscopy and pH electrode respectively. Cell mitochondrial function was measured by MTT assay. Type I cements suppressed mitochondrial activity > 90% (vs. Teflon controls), but significantly (p < 0.05) improved to control levels over 8 weeks. Type II cements suppressed mitochondrial activity > 90% at all times. Type III cements elevated mitochondrial activity significantly after 7 wks. The pH profiles approached neutrality by 24 h, and all cements released calcium into the storage medium at all periods (24 h - 8 wk). We concluded that several types of cements had long-term biological profiles that show promise for dental applications.

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The investigation of biocompatibility and apical microleakage of tricalcium phosphate based root canal sealers

Cited by 26 publications

References 14 publications

Interfacial adaptation and thickness of bioceramic-based root canal sealers

Interfacial adaptation and thickness of bioceramic-based root canal sealers

Evaluation of the cytotoxicity of calcium phosphate root canal sealers

Cytotoxicity, calcium release, and pH changes generated by novel calcium phosphate cement formulations

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