The Investigation of Fluorescence Biothiol Sensor Properties of 2-(N-hexyl-carbazole-3'-yl)-4- formylpyridine

Abstract

The biothiol sensor properties of 2-(N-hexyl-carbazole-3'-yl)-4-formylpyridine molecule were examined. This probe has carbazole moiety as a fluorophore and aldehyde group as a recognition site. Three different biothiol molecules as an analytes were chosen that they are cysteine (Cys), homocysteine (Hcy) and glutathione (GSH). We monitored the adduct formation between probe and analyte (biothiols) by 1 H NMR, MS, UV-vis and PL Spectrometers.