The involvement of free radicals in burn injury: a review

Oxidative Stress Biomarkers and Adenosine Deaminase over the Alopecic Area of the Patients with Alopecia Areata

“…Consistent with this, MDA levels from the serum or the tissue of AA patients were elevated in all previous studies similar to Behcet's Disease (10,(12)(13)(14)26). Indeed, MDA is proportional to the degree of lipid peroxidation and is a gold standard for evaluating oxidative stress (20). Based on this, lipid peroxidation may be heavily involved in the pathobiology of AA.…”

“…Also, AA presents with infiltration of inflammatory cells that surround the hair follicle. This infiltrate commonly causes hair follicle destruction and abnormal keratinization (20). The intracellular production of ROS that leading to oxidative cellular damage is elevated by infiltrating inflammatory cells and also by synthesized cytokines.…”

The Pathogenesis of Vitiligo

“…SOD scavenges superoxide radicals and reduces their toxicity (converts O 2 -to O 2 and H 2 O 2 ) and catalase converts hydrogen peroxide (H 2 O 2 ) to oxygen (O 2 ) and water (H 2 O) (Ines et al, 2006). MDA is a product of lipid peroxidation and is an indicator of oxidative stress (Latha & Babu, 2001, Yildirim et al, 2004. Selenium is required for GPx activity and vitamins E and A are important in antioxidant activity.…”

Superoxide Dismutase-Loaded Solid Lipid Nanoparticles Prepared by Cold Homogenization Method: Characterization and Permeation Study Through Burned Rat Skin

“…These cyto-protective mechanisms, known as antioxidant defenses, include several enzyme systems designed to scavenge oxygen radicals and detoxify them. They exist in both the aqueous and membrane compartments of cells and can be either enzymatic or non-enzymatic antioxidants (3).…”