2023
DOI: 10.1002/brb3.3250
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The involvement of language‐associated networks, tracts, and cortical regions in frontotemporal dementia and amyotrophic lateral sclerosis: Structural and functional alterations

Marlene Tahedl,
Ee Ling Tan,
Rangariroyashe H. Chipika
et al.

Abstract: BackgroundLanguage deficits are cardinal manifestations of some frontotemporal dementia (FTD) phenotypes and also increasingly recognized in sporadic and familial amyotrophic lateral sclerosis (ALS). They have considerable social and quality‐of‐life implications, and adaptive strategies are challenging to implement. While the neuropsychological profiles of ALS–FTD phenotypes are well characterized, the neuronal underpinnings of language deficits are less well studied.MethodsA multiparametric, quantitative neur… Show more

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