The Iron Triangle of Familiarity for Severe Mental Illness, Developmental Coordination Disorder and Risk of Psychosis: Recognize to Prevent

Poletti, Michele

doi:10.1007/s40474-023-00286-4

Curr Dev Disord Rep

2023

DOI: 10.1007/s40474-023-00286-4

|View full text |Cite

The Iron Triangle of Familiarity for Severe Mental Illness, Developmental Coordination Disorder and Risk of Psychosis: Recognize to Prevent

Michele Poletti

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 69 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Ontogenesis of self-disorders in the schizophrenia spectrum: A phenomenological neuro-developmental model

Poletti,

Raballo

2024

Schizophrenia Research

View full text Add to dashboard Cite

Ontogenesis of self-disorders in the schizophrenia spectrum: A phenomenological neuro-developmental model

Poletti,

Raballo

2024

Schizophrenia Research

View full text Add to dashboard Cite

Language, Motor Ability and Related Deficits in Children at Familial Risk of Schizophrenia or Bipolar Disorder

Schiavon,

Burton,

Hemager

et al. 2024

Schizophrenia Bulletin

View full text Add to dashboard Cite

Background It is known that impairments in linguistic ability and motor function tend to co-occur in children, and that children from families with parental mental illness such as schizophrenia tend to perform poorly in both domains, but the exact nature of these links has not yet been fully elucidated. Design In this study, we leveraged the first wave of the Danish High Risk and Resilience Study (VIA 7), which includes both genetic data and measures covering multiple developmental domains. The VIA 7 cohort comprises 522 7-year-old children born to parents with schizophrenia (N = 202), bipolar disorder (N = 120) or neither (N = 200). We investigated the relationships between linguistic ability and motor function using correlation and regression analyses, focusing on developmental coordination disorder (DCD) and specific language impairment (SLI) and their potential associations with the three risk groups. Results We found significant correlations between most measures of language and motor function and significant associations of DCD and SLI with language and movement measures, respectively, the largest effect being that of DCD on receptive language, with a significant interaction effect: DCD was associated with poorer performance in children from schizophrenia families compared to bipolar disorder and control families. Both disorders showed higher prevalence among children with familial high risk of mental illness. We did not find significant evidence of genetic overlap between DCD and SLI. Conclusions Our results suggest strong links between the domains of motor function and linguistic ability. Children of parents with schizophrenia are at high risk of comorbid language and movement disorders.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

The Iron Triangle of Familiarity for Severe Mental Illness, Developmental Coordination Disorder and Risk of Psychosis: Recognize to Prevent

Cited by 2 publications

References 69 publications

Ontogenesis of self-disorders in the schizophrenia spectrum: A phenomenological neuro-developmental model

Ontogenesis of self-disorders in the schizophrenia spectrum: A phenomenological neuro-developmental model

Language, Motor Ability and Related Deficits in Children at Familial Risk of Schizophrenia or Bipolar Disorder

Contact Info

Product

Resources

About