The Isolated Humeral Metastasis as the Initial Presentation of Renal Cell Carcinoma Revealed by 18F-FDG PET/CT

Hou, Guozhu; Zhang, Wenjie; Zheng, Rong

doi:10.1097/rlu.0000000000004633

Cited by 1 publication

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“…As a note, there were several differences between humerus metastasis and femur metastasis despite of their similarities. Femur metastasis was much more common in clinic while humerus metastasis was relatively rare, especially as isolated or initial metastatic site [ 32 , 33 ]. In a retrospectively study focusing on metastasis in long bones, the proportion of patients suffered from femur metastasis was up to 73.7% (84 cases) while the proportion was 22.8% in humerus metastasis [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

Ten-year retrospect of the investigation of proximal limbs metastasis in cancer: a multi-center study on survival outcome, limb function status and surgical procedures analysis

Zhang,

Wang,

et al. 2023

BMC Cancer

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Background The aim of study was to evaluate survival outcome and limb function in cancer patients with proximal limbs metastasis. Associated factors on survival outcome and limb function were identified. The comparative analysis between intramedullary nailing and prosthesis surgery in cancer patients with proximal limb metastasis was performed. Methods In this five-center retrospective study, patients diagnosed with limbs metastasis were collected. Descriptive statistics was used and log-rank test was performed to analyze the survival in subgroups. The Cox proportional hazards regression analysis was performed to identify the independent prognostic factors. The Musculoskeletal Tumor Society (MSTS) scoring system was used to evaluate limb function after surgery, and t test or analysis of variance (ANOVA) was utilized in subgroup analysis. Results A total of 316 patients with limb metastasis were included with mean age at 61.0 years. The most common primary tumor was breast, followed by renal cancer and lung cancer. The median overall survival was 24.0 months and the 1-, 3- and 5-year survival rates were 86.9%, 34.7% and 6.8%, respectively. Primary tumor type, visceral metastasis and chemotherapy were proved to be the independent prognostic factors. The mean Musculoskeletal Tumor Society (MSTS) score was 20.5, significant difference was observed in subgroup of solitary/multiple bone metastasis, with/without pathological fracture, and type of surgery. Conclusion The present study concluded that primary tumor type, visceral metastasis and chemotherapy were three factors affecting the survival of patients. Compared with intramedullary nailing, the patients underwent prosthesis surgery showed better limb function, this procedure should be encouraged in patients with indication.

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Section: Discussionmentioning

confidence: 99%