The kinetics and mechanisms of reactions in the flow systems glycine–sodium trimetaphosphate–imidazoles: the crucial role of imidazoles in prebiotic peptide syntheses

Prebiotic Chemistry: The Role of Trimetaphosphate in Prebiotic Chemical Evolution

“…All of the above evidences infer the existence of polyphosphates before the existence of living matter, and promotes the occurrence of chemical reactions and the evolution of life. Furthermore, numerous investigations into the phosphorylation and polymerization of biomolecules and polyphosphates have been conducted in this area ( Ponnamperuma et al, 1963b ; Schwartz and Fox, 1964 ; Ponnamperuma and Mack, 1965 ; Ferris, 1968 ; Fox and Waehneldt, 1968 ; Lohrmann and Orgel, 1968 ; Rabinowitz et al, 1968 ; Schwartz and Ponnamperuma, 1968 ; Rabinowitz et al, 1969 ; Rabinowitz, 1970 ; Lohrmann and Orgel, 1971 ; Handschuh et al, 1973 ; Lohrmann, 1975 ; Hulshof and Ponnamperuma, 1976 ; Schoffstall, 1976 ; Yamagata et al, 1979 ; Yamanaka et al, 1988 ; Schwartz, 2006 ; Holm and Baltscheffsky, 2011 ; Kee and Monnard, 2017 ; Christ et al, 2020 ; Serov et al, 2020 ; Brunk and Marshall, 2021 ; Glonek, 2021 ; Ying et al, 2021 ).…”