The Kisspeptin analogue C6 induces ovulation in jennies

GnRH analogue triptorelin acetate induces ovulation in jennies during oestrus

“…In this new productive view, the donkey assisted reproductive techniques started to develop with several studies focusing on oestrous and ovulation synchronization (Fanelli et al, 2018(Fanelli et al, , 2019Liu et al, 2020;Yang et al, 2018;Zhou et al, 2018) to optimize the reproductive management of the donkey farms with timed artificial insemination and embryo transfer. To induce ovulation in the jenny hCG, GnRH analogues (Camillo et al, 2014;Carluccio et al, 2007;Liu et al, 2020) and Kisspeptin (Fanelli et al, 2022) have been used.…”

“…In this new productive view, the donkey assisted reproductive techniques started to develop with several studies focusing on oestrous and ovulation synchronization (Fanelli et al., 2018, 2019; Liu et al., 2020; Yang et al., 2018; Zhou et al., 2018) to optimize the reproductive management of the donkey farms with timed artificial insemination and embryo transfer. To induce ovulation in the jenny hCG, GnRH analogues (Camillo et al., 2014; Carluccio et al., 2007; Liu et al., 2020) and Kisspeptin (Fanelli et al., 2022) have been used. Kisspeptin is for experimental use only and the use of hCG presents the limit of a reduction in its efficacy after repeated injections in the mare (Wilson et al., 1990), even though no studies have been performed to assess this effect in the jenny, clinical research is mostly focused on to GnRH analogues.…”

“…and kisspeptin (Fanelli et al, 2022) during oestrus, with ovulatory rates from 67 to 100% (Camillo et al, 2014;Carluccio et al, 2007;Yang et al, 2017). Buserelin acetate was the only inducing GnRH analogue tested at different doses in the jenny (Camillo et al, 2014), showing that the minimum effective dose was 0.04 mg/sc.…”

“…A relatively significant number of studies was recently performed on donkey ovulation synchronization (Fanelli et al., 2018, 2019; Liu et al., 2020; Yang et al., 2018; Zhou et al., 2018) as a consequence of the increased interest in donkeys as a farm animal producing milk (Martini et al., 2014) or donkey hide gelatin (Lesté‐Lasserre, 2019; Yang et al., 2018). Ovulation induction was performed using hCG, GnRH analogues (Lecirelin, Buserelin, and Deslorelin) (Camillo et al., 2014; Carluccio et al., 2007; Liu et al., 2020) and kisspeptin (Fanelli et al., 2022) during oestrus, with ovulatory rates from 67 to 100% (Camillo et al., 2014; Carluccio et al., 2007; Yang et al., 2017). Buserelin acetate was the only inducing GnRH analogue tested at different doses in the jenny (Camillo et al., 2014), showing that the minimum effective dose was 0.04 mg/sc.…”