Dedicated with great pleasure to Yuri Latushkin on the occasion of his 60th birthday.
Abstract.For an arbitrary open, nonempty, bounded set Ω ⊂ R n , n ∈ N, and sufficiently smooth coefficients a, b, q, we consider the closed, strictly positive, higher-order differential operator A Ω,2m (a, b, q) in L 2 (Ω) defined on W 2m,2 0 (Ω), associated with the higher-order differential expressionand its Krein-von Neumann extension A K,Ω,2m (a, b, q) in L 2 (Ω). Denoting by N (λ; A K,Ω,2m (a, b, q)), λ > 0, the eigenvalue counting function corresponding to the strictly positive eigenvalues of A K,Ω,2m (a, b, q), we derive the boundwhere C = C(a, b, q, Ω) > 0 (with C(In, 0, 0, Ω) = |Ω|) is connected to the eigenfunction expansion of the self-adjoint operator A 2m (a, b, q) in L 2 (R n ) defined on W 2m,2 (R n ), corresponding to τ 2m (a, b, q). Here vn := π n/2 /Γ((n + 2)/2) denotes the (Euclidean) volume of the unit ball in R n .Our method of proof relies on variational considerations exploiting the fundamental link between the Krein-von Neumann extension and an underlying abstract buckling problem, and on the distorted Fourier transform defined in terms of the eigenfunction transform of A 2 (a, b, q) in L 2 (R n ).We also consider the analogous bound for the eigenvalue counting function for the Friedrichs extension A F,Ω,2m (a, b, q) in L 2 (Ω) of A Ω,2m (a, b, q).No assumptions on the boundary ∂Ω of Ω are made. Date: July 4, 2018. 2010 Mathematics Subject Classification. Primary 35J25, 35J40, 35P15; Secondary 35P05, 46E35, 47A10, 47F05.Key words and phrases. Krein and Friedrichs extensions of general second-order uniformly elliptic partial differential operators, bounds on eigenvalue counting functions, spectral analysis, buckling problem.