Let M (2,1) (N ) denotes the infimum of the size of the largest sum-free subset of any set of N positive integers. An old conjecture in additive combinatorics asserts that there are a constant c = c(2, 1) and a function ωis determined by Eberhard, Green, and Manners, while the existence of ω(N ) is still widely open.In this paper, we study the analogue conjecture on (k, ℓ)-sum free sets and restricted (k, ℓ)-sum free sets. We determine the constant c(k, ℓ) for every (k, ℓ), and confirm the conjecture for infinitely many (k, ℓ).