The LASSO Program in Oslo: Harm Reduction Using Buprenorphine-Naloxone (Suboxone®) in a Low Threshold Setting

Henriksen, Kathleen; Jacobsen, Jon-Aksel; Henriksen, Elliott Magnus; Gomes, Leni; Waal, Helge; Krajči, Peter

doi:10.1159/000495188

Cited by 12 publications

(8 citation statements)

References 10 publications

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“…In France, deaths due to methadone are increasing, while those due to buprenorphine remain stable [27]. The use of buprenorphine has been found safe even in low threshold setting [28].…”

Section: Discussionmentioning

confidence: 99%

Primary Care of Opioid use Disorder: The End of “the French Model”?

Dupouy¹,

Maumus-Robert²,

Mansiaux³

et al. 2020

Eur Addict Res

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Background: In France, most patients with opioid use disorder (OUD) have been treated by buprenorphine, prescribed by general practitioners (GP) in private practice since 1996. This has contributed to building a 'French model' facilitating access to treatment based on the involvement of GPs in buprenorphine prescription. Objectives: Our study aimed to assess whether the involvement of primary care in OUD management has changed lately. Materials and Methods: Using data from the French National Health Insurance database, we conducted a yearly repeated crosssectional study (2009-2015) and described proportion of opioid maintenance treatment (OMT)-prescribing GPs and OMT-dispensing community pharmacies (CP); and number of patients by GP or CP. Results: Whereas the number of buprenorphine-prescribing GPs in private practice remained quite stable (decrease of 3%), a substantial decrease in buprenorphine initial prescribers among private GPs was observed. In 2009, 10.3% of private GPs (6,297 from 61,301 French private GPs) prescribed buprenorphine for the initiation of a treatment, whereas they were 5.7% (n = 3,539 from 62,071 private GPs) in 2015 (43.8% decrease). GPs issuing initial prescriptions of buprenorphine tended to care for a higher number of patients treated by buprenorphine (14.6 ± 27.1 patients in 2009 to 16.0 ± 35.4 patients in 2015). The number of CPs dispensing buprenorphine remained quite stable (decrease of 2%), while there was a 7.5% decrease in the total number of French CPs across the study period. Conclusions: Our results suggest that primary care providers seem less engaged in buprenorphine initiation in OUD patients, while CPs have not modified their involvement towards these patients.

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“…In France, deaths due to methadone are increasing, while those due to buprenorphine remain stable [27]. The use of buprenorphine has been found safe even in low threshold setting [28].…”

Section: Discussionmentioning

confidence: 99%

Primary Care of Opioid use Disorder: The End of “the French Model”?

Dupouy¹,

Maumus-Robert²,

Mansiaux³

et al. 2020

Eur Addict Res

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“…We found few differences between drug users receiving treatment and those not receiving treatment and are thus unable to point to specific attributes in the group not receiving treatment that could have aided clinicians and social workers into recruiting this group into treatment. [44,45] and the addition of assertive community treatment (ACT) may with further research lead to valuable strategies for recruitment [46].…”

Section: Limitationsmentioning

confidence: 99%

Treatment Status and Use of Psychoactive Substances in Deceased Drug Users

et al. 2019

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Background: Studies on drug use are limited by the study populations available, which usually only include drug users in treatment settings. Therefore, the knowledge base is limited on drug users not entering treatment for drug use disorder (DUD). Using registers from departments of forensic medicine enables research on decedents with DUD, irrespective of treatment status. Objectives: The aim of this study is to characterise and compare drug users not receiving treatment and drug users receiving treatment, in relation to cause of death, toxicological findings and use of non-prescribed medication.

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“…Patients with severe ongoing addiction-related problems can be "hard to reach" and have limited contact with specialized health services (47). OMT has been shown to be effective in such "hard to reach" patients in low-threshold setting with regard to harm reduction purposes (47).…”

Section: Retention In Treatmentmentioning

confidence: 99%