The Late Course of Acute Partial Anterior Cruciate Ligament Tears

Sommerlath, Karola; Odensten, Magnus; Lysholm, Jack

doi:10.1097/00003086-199208000-00025

Cited by 45 publications

(36 citation statements)

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“…This result was unchanged at the long-term follow-up visit at twenty years after the initial injury 39 . Sommerlath et al reported that, of twenty-two patients available for arthrometric testing, 86% (nineteen) had an increase in laxity of <3 mm 52 .…”

Section: Arthrometric Testingmentioning

confidence: 99%

“…Some surgeons have found a correlation between the amount of injury visualized at the time of arthroscopy and the clinical outcome 9 , but others have not 11,52,61 . This discrepancy reflects the imprecision of the arthroscopic grading of anterior cruciate ligament tears and indicates that a torn but functional ligament cannot always be identified with arthroscopy.…”

Section: Arthroscopymentioning

confidence: 99%

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A Comprehensive Review of Partial Anterior Cruciate Ligament Tears

DeFranco

Bach

2009

The Journal of Bone and Joint Surgery-American Volume

149

117

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A partial tear of the anterior cruciate ligament is characterized by an asymmetric Lachman-test result, a negative pivot-shift test, a low-grade KT-1000 arthrometer measurement (< or =3 mm), and arthroscopic evidence of anterior cruciate ligament injury. The pivot shift test is the most important test in determining anterior cruciate ligament insufficiency. A positive test, independent of the grade, is indicative of a functionally deficient anterior cruciate ligament. Nonoperative management results in an acceptable clinical outcome in the majority of cases. Progression to knee instability (anterior translation and rotation) depends on the extent of the anterior cruciate ligament injury and the activity level of the patient. Thermal treatment is not recommended for partial tears of the anterior cruciate ligament. Symptomatic instability is treated reliably with anterior cruciate ligament reconstruction.

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Section: Arthrometric Testingmentioning

confidence: 99%

Section: Arthroscopymentioning

confidence: 99%

A Comprehensive Review of Partial Anterior Cruciate Ligament Tears

DeFranco

Bach

2009

The Journal of Bone and Joint Surgery-American Volume

149

117

View full text Add to dashboard Cite

show abstract

“…15,45 There is a controversy related to the relationship between the management of ACL injury and the development of OA. Daniel 18 reported a higher occurrence of OA in surgically treated, compared to conservatively treated, patients with an ACL injury; conversely, Lynch et al 62 and Sommerlath et al 89 reported a higher incidence in the ACL deficient knee (not reconstructed). Reportedly, 70% to 85% of all ACL injuries involve a concurrent bone bruise (Figure 1), an injury to the articular cartilage and subchondral bone 30,34,43,44,90,91 that must be returned to homeostasis.…”

Section: Effects Of Specific Knee Injuriesmentioning

confidence: 98%

Rehabilitation of Articular Lesions in the Athlete's Knee

Wilk

Briem²,

Reinold³

et al. 2006

J Orthop Sports Phys Ther

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Articular cartilage lesions of the knee joint are common in patients of varying ages. Some articular cartilage lesions are focal lesions located on one aspect of the tibiofemoral or patellofemoral joint. Other lesions can be extremely large or involve multiple compartments of the knee joint and these are often referred to as osteoarthritis. There are numerous potential causes for the development of articular cartilage lesions: joint injury (trauma), biomechanics, genetics, activities, and biochemistry. Numerous factors also contribute to symptomatic episodes resulting from lesions to the articular cartilage: activities (sports and work), joint alignment, joint laxity, muscular weakness, genetics, dietary intake, and body mass index. Athletes appear to be more susceptible to developing articular cartilage lesions than other individuals. This is especially true with specific sports and subsequent to specific types of knee injuries. Injuries to the anterior cruciate ligament and/or menisci may increase the risk of developing an articular cartilage lesion. The treatment for an athletic patient with articular cartilage lesions is often difficult and met with limited success. In this article we will discuss several types of knee articular cartilage injuries such as focal lesions, advanced full-thickness lesions, and bone bruises. We will also discuss the risk factors for developing full-thickness articular cartilage lesions and osteoarthritis, and describe the clinical evaluation and nonoperative treatment strategies for these types of lesions in athletes.

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“…In a prospective study, Noyes et al estimated that 50% of patients with partial tears affecting more than half of the ACL progressed to complete ACL insufficiency after non-operative treatment 9 . Other studies report persistent instability and decreased function with fewer than 30% of patients able to return to their pre-injury activity level 9,10,11,12,13 . Treatment options are limited and include conservative modalities, thermal shrinkage of remaining ACL, or ACL reconstruction.…”

Section: Introductionmentioning

confidence: 99%

Surgical Retrieval, Isolation and <em>In vitro</em> Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications

Gupta

Sharif

Walters

et al. 2014

JoVE

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Injury to the ACL is a commonly encountered problem in active individuals. Even partial tears of this intra-articular knee ligament lead to biomechanical deficiencies that impair function and stability. Current options for the treatment of partial ACL tears range from nonoperative, conservative management to multiple surgical options, such as: thermal modification, single-bundle repair, complete reconstruction, and reconstruction of the damaged portion of the native ligament. Few studies, if any, have demonstrated any single method for management to be consistently superior, and in many cases patients continue to demonstrate persistent instability and other comorbidities.The goal of this study is to identify a potential cell source for utilization in the development of a tissue engineered patch that could be implemented in the repair of a partially torn ACL. A novel protocol was developed for the expansion of cells derived from patients undergoing ACL reconstruction. To isolate the cells, minced hACL tissue obtained during ACL reconstruction was digested in a Collagenase solution. Expansion was performed using DMEM/F12 medium supplemented with 10% fetal bovine serum (FBS) and 1% penicillin/streptomycin (P/ S). The cells were then stored at -80 ºC or in liquid nitrogen in a freezing medium consisting of DMSO, FBS and the expansion medium. After thawing, the hACL derived cells were then seeded onto a tissue engineered scaffold, PLAGA (Poly lactic-co-glycolic acid) and control Tissue culture polystyrene (TCPS). After 7 days, SEM was performed to compare cellular adhesion to the PLAGA versus the control TCPS. Cellular morphology was evaluated using immunofluorescence staining. SEM (Scanning Electron Microscope) micrographs demonstrated that cells grew and adhered on both PLAGA and TCPS surfaces and were confluent over the entire surfaces by day 7. Immunofluorescence staining showed normal, non-stressed morphological patterns on both surfaces. This technique is promising for applications in ACL regeneration and reconstruction.

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The Late Course of Acute Partial Anterior Cruciate Ligament Tears

Cited by 45 publications

References 0 publications

A Comprehensive Review of Partial Anterior Cruciate Ligament Tears

A Comprehensive Review of Partial Anterior Cruciate Ligament Tears

Rehabilitation of Articular Lesions in the Athlete's Knee

Surgical Retrieval, Isolation and <em>In vitro</em> Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications

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