The Level of Iodine in the Blood

Blood Iodine in Patients With Thyroid Disease 1

“…The lack of overlapping with the normal figures in the present study makes it improbable that a normal blood iodine will be found in a larger series of patients with hyperthyroidism. In view of the reports of Perkin and his associates (10,11,12) (4,15,16), by Grauer and Saier (3) and by Baumann and Metzger (2). The results of the latter workers were cited above.…”

Endocrine Review: THE CLINICAL SIGNIFICANCE OF THE BLOOD IODINE: A REVIEW*

“…This is contradicted by at least one investigator (127). Other reports (27,121,128,129) fail to find any seasonal variation. These investigations, however, have all been carried out on total blood iodines.…”

“…It appears that the level of the blood iodine is not significantly altered in different age groups (27,121).…”

“…Perkin and Lahey (27) in 1940 pointed out that the numerous methods of analysis reported in the literature up until that time (8, 9, 15, 17, 20, 26 and 28-54) gave ample evidence in support of the conclusion that the quantitative estimation of the iodine content of blood was not an easy procedure. To the 33 methods listed above may be added at least 26 more, some developed before and others since that time (10, 11, 13, 21-25 and 55-72).…”

“…At least one investigator could determine no fluctuation in the blood iodine during the menstrual cycle (136). Perkin concludes that the variation attributed to menses is not consistent to a degree applicable in all instances (27).…”