The levels of oxidative stress in a combination of stress factors

Abstract

We studied the effect of the combined action of ionizing radiation and induced immobilization stress on the lipid peroxidation process and antioxidant protection of organs (mesenteric lymph nodes, spleen, adrenal glands, thymus, and liver) and immune cels - the blood lymphocytes. Results were obtained on the role of free-radical oxidation in combination with exposure to ionizing radiation and immobilization stress at an early stage in the experiment. Gamma radiation in the acute period resulted in significant changes in lipoperoxidation and antioxidant systems. The first period of immobilization stress was marked by the imbalance of LPO-AOS systems disturbance with an accumulation of toxic compounds in tissues which had affected their function. The combined sublethal gamma radiation and immobilization stress disturbed the functional activity of adaptive systems of the body in the early stage of adaptation syndrome. Furthermore, the results show the dominant role of ionizing radiation in it.

Manganese Nanoparticles: Synthesis, Mechanisms of Influence on Plant Resistance to Stress, and Prospects for Application in Agricultural Chemistry

“…102 During the LP process, primary and secondary metabolites are formed such as conjugated dienes (CDs) and malonic dialdehyde (MDA), respectively. 103 LP products are toxic compounds that alter the functional properties of biopolymers. 104 The stabilizers of the LP reaction are antioxidant system processes, which are normally mediated by endo-and exogenous antioxidants of enzymatic and nonenzymatic nature, which interrupt free radical oxidation reactions.…”

“…LP causes oxidative degradation of lipids in the cell membrane, leads to the oxidation of protein SH groups, and inhibits the synthesis of proteins and enzymes, which provokes cell death . During the LP process, primary and secondary metabolites are formed such as conjugated dienes (CDs) and malonic dialdehyde (MDA), respectively . LP products are toxic compounds that alter the functional properties of biopolymers .…”

“…104 The stabilizers of the LP reaction are antioxidant system processes, which are normally mediated by endo-and exogenous antioxidants of enzymatic and nonenzymatic nature, which interrupt free radical oxidation reactions. 103 It is known that NPs of metals and metal oxides are capable of possessing both pro-oxidant and antioxidant activities in plant cells. 105,106 Thus, NPs are able to enhance the generation of ROS.…”

“…LP products are toxic compounds that alter the functional properties of biopolymers . The stabilizers of the LP reaction are antioxidant system processes, which are normally mediated by endo- and exogenous antioxidants of enzymatic and nonenzymatic nature, which interrupt free radical oxidation reactions …”

Correction to: The levels of oxidative stress in a combination of stress factors

“…In the original publication [ 1 ], two author names: Assem Musaynova and Gulmira Zharmakhanova, and two affiliations were omitted. The original article is now corrected.…”