The Lifetime Risk of Suicide in Schizophrenia

Palmer, Brian A.; Pankratz, V. Shane; Bostwick, John

doi:10.1001/archpsyc.62.3.247

Cited by 892 publications

(535 citation statements)

References 71 publications

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“…This is in accordance with previous findings that suicide risk changes with time and suicide ideation occurs mostly early in the course of illness (Palmer et al, 2005;Nordentoft et al, 2004). Suicide ideators and attempters were mostly men with lower level of education and retired due to illness.…”

Section: Discussionsupporting

confidence: 93%

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Suicide ideators and attempters with schizophrenia – The role of 5-HTTLPR, rs25531, and 5-HTT VNTR Intron 2 variants

Božina

Jovanović

Podlešek

et al. 2012

Journal of Psychiatric Research

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Section: Discussionsupporting

confidence: 93%

“…Today suicide is the leading cause of premature death in schizophrenia with approximately 5% completing suicide. (Inskip et al, 1998, Palmer et al, 2005.…”

Section: Introductionmentioning

confidence: 99%

Suicide ideators and attempters with schizophrenia – The role of 5-HTTLPR, rs25531, and 5-HTT VNTR Intron 2 variants

Božina

Jovanović

Podlešek

et al. 2012

Journal of Psychiatric Research

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“…Even though the mechanisms underlying suicidal behaviour remain poorly understood, research has shown that it is likely determined by a complex interplay of biological, psychological, environmental and cultural factors (O'Connor et al, 2011;World Health Organization, 2014). Mental disorders are an important risk factor for suicidal behaviour (Bostwick and Pankratz, 2000;Nordentoft et al, 2011;Palmer et al, 2005): of the individuals who committed suicide, 91% had a mental disorder, most commonly a depressive disorder, substance abuse or schizophrenia (Cavanagh et al, 2003;ten Have et al, 2009;Ten Have et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Psychotic experiences and incident suicidal ideation and behaviour: Disentangling the longitudinal associations from connected psychopathology

Honings

Drukker

Nierop

et al. 2016

Psychiatry Research

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Psychotic experiences and incident suicidal ideation and behaviour 2 ABSTRACT This study examines the longitudinal associations between psychotic experiences (PE) and incident suicidal ideation and behaviour in the general population, and to what degree the association may be confounded by nonpsychotic psychopathology. Data from three prospective, general population cohorts were combined into one dataset (n=15837) and analysed using logistic regression, controlling for continuous measures of depression, anxiety and mania symptoms. Analyses were conducted in the entire sample, and in subsamples stratified by presence or absence of mental disorders. The presence of PE at baseline increased the risk of incident suicidal ideation and behaviour. However, adjustment for dimensional measures of psychopathology reduced effect sizes, although PE remained significantly associated with suicide attempts. Further examination of the associations revealed that PE were only associated with suicide attempts in individuals with at least one mental disorder.Similarly, in individuals without mental disorders, the risk of suicidal ideation increased as PE co-occurred with more symptom domains. The results of this study confirm that individuals with PE are at increased risk of suicidal ideation and behaviour. However, these associations are not specific, but reflect the increased risk of suicidal ideation in individuals with subthreshold multidimensional psychopathology and suicide attempts in individuals with co-occurring mental disorders.

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“…In a recent meta analysis, Palmer et al (2005) have estimated that 4.9% of patients commit suicide during their lifetimes, usually around the time of onset of the illness. Suicidal risk increases with age (Bille-Brahe, 1993).…”

Section: Introductionmentioning

confidence: 99%

Differing correlates for suicide attempts among patients with schizophrenia or schizoaffective disorder in India and USA

Bhatia

Thomas

Semwal

et al. 2006

Schizophrenia Research

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Background-Suicide is one of the most common causes of death among persons with schizophrenia. Differing risk factors have been identified in published studies. The differences may have arisen because a uniform set of variables was not analyzed. Alternatively, the nature and effect of risk factors may vary in different settings. To test these possibilities, we investigated the same set of variables in two independent cross-national samples ascertained using identical protocols.Methods-Patients with schizophrenia or schizoaffective disorder (DSM IV criteria) were recruited in India (n=460) and the USA (n=424).Results-Consistent with earlier publications, a diagnosis of schizoaffective disorder, history of depression, pattern of symptoms and educational status were significantly associated with suicide attempts in the US sample. None of these variables were significantly associated in the Indian sample.Conclusions-The impact of known risk factors for suicide attempts among patients with schizophrenia differs across ethnic groups.

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The Lifetime Risk of Suicide in Schizophrenia

Abstract: This study estimates that 4.9% of schizophrenics will commit suicide during their lifetimes, usually near illness onset.

Cited by 892 publications

References 71 publications

Suicide ideators and attempters with schizophrenia – The role of 5-HTTLPR, rs25531, and 5-HTT VNTR Intron 2 variants

Suicide ideators and attempters with schizophrenia – The role of 5-HTTLPR, rs25531, and 5-HTT VNTR Intron 2 variants

Psychotic experiences and incident suicidal ideation and behaviour: Disentangling the longitudinal associations from connected psychopathology

Differing correlates for suicide attempts among patients with schizophrenia or schizoaffective disorder in India and USA

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