“…Historically, in 1912, Huggins wrote an article recognizing that Sippel proposed resection of the ovarian vein and uterus in 1894 [11]. Then, Freund was the first to resect the ovarian vein in patients with POVT in 1898, and Trendelenburg performed the first successful resection of the ovarian vein in 1902 [11]. However, since the advent of antibiotics and anticoagulants in the 1940s, POVT treatment has gradually shifted from surgical intervention to medical therapy.…”