BackgroundRural primary care practices struggle to employ and retain staff, and existing literature regarding recruitment and retention is focussed on doctors. Shortages of qualified staff affect practice functioning, quality of care and patient experience. Dispensing of medications is a rural service valued by patients. However, little is known about how dispensing services are valued by practices or related to the recruitment and retention of staff.AimTo understand barriers to, and facilitators of, joining, and remaining in, rural dispensing practice employment, and to explore how rural practices value dispensing services.Design & settingQualitative inquiry in rural primary care practices across England.MethodSemi-structured interviews with rural dispensing staff were undertaken, audio-recorded, transcribed verbatim and analysed using framework analysis.Results17 staff from 12 practices across England were interviewed between June and November 2021. Reasons for taking up employment in rural dispensing practices included perceived career autonomy, development opportunities, and preference for working and living in a rural setting. Skills required for dispensers’ roles balanced against low wages were a barrier to recruitment. For nurses, barriers included perceived lack of knowledge around their role in rural care. Revenue from dispensing, opportunities for staff development, job satisfaction and positive work environments drove retention of staff. However, negative perceptions of rural practice, travel difficulties, lack of applicants and insufficient remuneration for roles were barriers to retention.ConclusionsBarriers to, and facilitators of, rural primary care recruitment and retention vary by role, and include factors unique to the rural setting.