The Literature of Heterocyclic Chemistry, Part XII, 2010–2011

Беленький, Л. И.; Evdokimenkova, Yu. B.

doi:10.1016/b978-0-12-420160-6.00004-5

Cited by 18 publications

(1 citation statement)

References 1,299 publications

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“…Pyridones and substituted pyridones are important family of heterocyclic compounds as they have attracted significant interest in medicinal chemistry in recent years [6] due to their broad spectrum of biological activities, such as anti-inflammatory [7] antifungal [8] anticancer [9], antibacterial [10], antiviral [11], antidepressant, [12], antidiabetic [13] and antioxidant [14] activities.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, biological evaluation and molecular modeling of novel series of pyridine derivatives as anticancer, anti-inflammatory and analgesic agents

Helal

Awdan²,

Salem

et al. 2015

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Section: Introductionmentioning

confidence: 99%

Synthesis, biological evaluation and molecular modeling of novel series of pyridine derivatives as anticancer, anti-inflammatory and analgesic agents

Helal

Awdan²,

Salem

et al. 2015

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Synthesis of Alkyl‐Substituted Pyrazine N‐Oxides by Transition‐Metal‐Free Oxidative Cross‐Coupling Reactions

Lai

et al. 2018

Asian J Org Chem

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Direct access to alkyl-substituted pyrazine Noxides has been accomplished through an intermolecular dehydrogenative cross-couplingr eaction of ethers and pyrazine N-oxides in the presence of tert-butyl hydroperoxide (TBHP). This approach successfully provided av ariety of alkyl-substituted pyrazine N-oxides in up to 96 %y ield. Thermogravimetric analysis indicates that the degradation tem-perature of C2-alkyated product 3a is approximately 263 8C. Under pyrolysisc onditions, 3a generated several compoundss uch as 2,5-dimethylpyrazine, 2,3,5-trimethylpyrazine, and 3-ethyl-2,5-dimethylpyrazine, which are characterized by their distinct aromas. The results of the pyrolysis experiment support the use of these compounds as possible flavor additives.

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Synthesis of Aza‐Heteroaromatic Dithiocarbamates via Cross‐Coupling Reactions of Aza‐Heteroaromatic Bromides with Tetraalkylthiuram Disulfides

et al. 2019

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The preparation of various aza‐heteroaromatic dithiocarbamates from aza‐heteroaromatic bromides and tetraalkylthiuram disulfides is reported. The transformation provides a convenient procedure, with good yields and functional group tolerance to various important nitrogen‐containing heteroaromatic dithiocarbamates such as benzothiazole, quinoline, pyridine, and pyrazine motifs. This protocol allows the facile synthesis of some potential biologically active compounds.

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The Literature of Heterocyclic Chemistry, Part XII, 2010–2011

Cited by 18 publications

References 1,299 publications

Synthesis, biological evaluation and molecular modeling of novel series of pyridine derivatives as anticancer, anti-inflammatory and analgesic agents

Synthesis, biological evaluation and molecular modeling of novel series of pyridine derivatives as anticancer, anti-inflammatory and analgesic agents

Synthesis of Alkyl‐Substituted Pyrazine N‐Oxides by Transition‐Metal‐Free Oxidative Cross‐Coupling Reactions

Synthesis of Aza‐Heteroaromatic Dithiocarbamates via Cross‐Coupling Reactions of Aza‐Heteroaromatic Bromides with Tetraalkylthiuram Disulfides

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