The long-lasting effects of the acute respiratory distress syndrome

Mart, Matthew F.; Ware, Lorraine B.

doi:10.1080/17476348.2020.1743182

Cited by 48 publications

(34 citation statements)

References 85 publications

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“…Persisting cardiorespiratory symptoms may be in part related to initial disease severity and residual organ damage. In critically ill patients, acute respiratory distress (ARDS) – related consequences have been described previously ( Desai et al, 1999 ; Mart and Ware, 2020 ) and are not specific to COVID-19. Other ICU-related complications such as ventilator-induced lung injury or critical illness-associated poly-neuropathy are well established ( Zhou et al, 2014 ; Beitler et al, 2016 ) and are out of the scope of this article.…”

Section: Persisting Cariorespiratory Symptoms In Coronavirus Survivormentioning

confidence: 99%

“…The extent and severity of the lasting sequelae remain to be evaluated, but persisting cardiorespiratory symptoms in COVID-19 survivors can be described as two distinct entities. The first type of post-Covid consequences are directly related to organ damage in the acute phase, either due to the viral infection and the ensuing inflammatory response, or the complications of treatment in the intensive care setting ( Li et al, 2006 ; Zhou et al, 2014 ; Mart and Ware, 2020 ). The persisting cardiorespiratory symptoms related to cardiac and lung injury in COVID-19 will be summarized below.…”

Section: Introductionmentioning

confidence: 99%

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Hyperventilation: A Possible Explanation for Long-Lasting Exercise Intolerance in Mild COVID-19 Survivors?

et al. 2021

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Since the outbreak of the coronavirus (COVID-19) pandemic, most attention has focused on containing transmission and addressing the surge of critically ill patients in acute care settings. As we enter the second phase of the pandemic, emphasis must evolve to post-acute care of COVID-19 survivors. Persisting cardiorespiratory symptoms have been reported at several months after the onset of the infection. Information is lacking on the pathophysiology of exercise intolerance after COVID-19. Previous outbreaks of coronaviruses have been associated with persistent dyspnea, muscle weakness, fatigue and reduced quality of life. The extent of Covid-19 sequelae remains to be evaluated, but persisting cardiorespiratory symptoms in COVID-19 survivors can be described as two distinct entities. The first type of post-Covid symptoms are directly related to organ injury in the acute phase, or the complications of treatment. The second type of persisting symptoms can affect patients even with mild initial disease presentation without evidence of organ damage. The mechanisms are still poorly qualified to date. There is a lack of correlation between initial symptom severity and residual symptoms at exertion. We report exercise hyperventilation as a major limiting factor in COVID-19 survivors. The origin of this hyperventilation may be related to an abnormality of ventilatory control, by either hyperactivity of activator systems (automatic and cortical ventilatory control, peripheral afferents, and sensory cortex) or failure of inhibitory systems (endorphins) in the aftermath of pulmonary infection. Hyperventilation-induced hypocapnia can cause a multitude of extremely disabling symptoms such as dyspnea, tachycardia, chest pain, fatigue, dizziness and syncope at exertion.

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Section: Persisting Cariorespiratory Symptoms In Coronavirus Survivormentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Hyperventilation: A Possible Explanation for Long-Lasting Exercise Intolerance in Mild COVID-19 Survivors?

et al. 2021

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“…Langtidsfølger av intensivbehandling generelt, også kalt post-intensive care syndrome (PICS), og av akutt lungesviktsyndrom (acute respiratory distress syndrome, ARDS) spesielt, har fått økende oppmerksomhet det siste tiåret (4). Vi har laert at kritisk sykdom medfører kroniske helseplager, resulterer i multimorbiditet og kan gi en rekke (lang)varige funksjonsnedsettelser innenfor alle biopsykososiale domener (1,5).…”

Section: Stort Behov For Helsetjenester Etter Akuttfasenunclassified

“…Langtidsfølgene av akutt lungesviktsyndrom inkluderer nedsatt kognitiv funksjon, psykososiale problemer (angst, depresjon), nevromuskulaer svakhet, nedsatt lungefunksjon og vedvarende bruk av helsetjenester (4). Til sammen medfører dette nedsatt livskvalitet.…”

Section: Stort Behov For Helsetjenester Etter Akuttfasenunclassified

Rehabilitering etter covid-19

Becker¹,

Laake²,

Hofsø³

2020

Tidsskriftet

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er klinikkoverlege ved Sunnaas sykehus og førsteamanuensis i fysikalsk medisin og rehabilitering ved Institutt for klinisk medisin ved Universitetet i Oslo. Han leder Fagråd rehabilitering i Helse Sør-Øst. Forfatteren har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter. JON HENRIK LAAKE Jon Henrik Laake er dr.med. og overlege ved intensivavdelingen på Rikshospitalet, ansatt ved Akuttklinikken ved Oslo universitetssykehus. Han er nestleder i Norsk anestesiologisk forening og leder av Acute respiratory failure task force i Scandinavian Society of Anaesthesiology and Intensive Care Medicine. Forfatteren har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter. KRISTIN HOFSØ Kristin Hofsø er intensivsykepleier, postdok ved Akuttklinikken ved Oslo universitetssykehus og førsteamanuensis ved Lovisenberg diakonale høgskole. Hun leder en nasjonal oppfølgingsstudie av covid-19-overlevere etter intensivopphold. Forfatteren har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter. Samfunnet gjør nå en stor innsats for at så mange som mulig skal overleve alvorlig covid-19sykdom. Jobben bør ikke slutte der-vi må også sørge for at de reddede livene blir så gode som mulig.

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“…The priority should be to implement immediate rehabilitation in post-infection patients (post-intensive care syndrome), as data from previous epidemics of respiratory-related viral diseases shows that COVID-19 survivors should be expected to have impaired lung ventilation function and reduced exercise tolerance, muscular weakness and, as a consequence a prolonged return to work after recovery or functional limitations in their work, decreased earning capacity, limited daily activities, a loss of independence, susceptibility to infections, and the presence of other comorbidities [8,9]. It should be assumed that only the introduction of immediate recommendations for the implementation of rehabilitation procedures based on simple and wellknown tests, as well as their obligatory regime, can contribute to the reduction of respiratory disability leading, in a short time, to infections recurrence and, in the long run, to a lower quality of life and socioeconomic burden on the population [10].…”

Section: Introductionmentioning

confidence: 99%

Post-COVID-19 rehabilitation – a Polish pilot program

Szczegielniak¹,

Bogacz²,

Majorczyk³

et al. 2021

Med Pr

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The current spread of SARS-CoV-2 indicates a long-term fight against the widespread and exponential increase in morbidity and mortality across the globe. A variety of non-pharmacological strategies to mitigate and suppress virus transmission have been investigated and introduced. Currently, emerging studies focus mostly on the management of hospital-treated patients in the acute phase of the disease, including the legitimacy of using physiotherapeutic procedures. However, current literature lacks guidelines for rehabilitation related to maintaining continuity and universality of the therapy after the end of the acute phase of the disease and discharge from hospital. The authors suggest implementing an immediate rehabilitation program in post-infection patients as data from previous epidemics of respiratory-related viral diseases shows that COVID-19 survivors should be expected to have impaired lung ventilation function, and reduced exercise tolerance and muscular weakness, and prolonged return to work and participation. It should be assumed that only the introduction of immediate recommendations for the implementation of rehabilitation procedures based on simple and well-known tests, as well as their obligatory regime, can contribute to the reduction of respiratory disability leading, in a short time, to infections recurrence and, in the long run, to a lower quality of life and socioeconomic burden on the population. This article presents a respiratory rehabilitation program for COVID-19 survivors, recommended by the Polish Society of Physiotherapy. This program was approved by the Polish Minister of Health and implemented as a pilot program at the Hospital of the Ministry of the Interior and Administration in Głuchołazy, Poland. Med Pr. 2021;72

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The long-lasting effects of the acute respiratory distress syndrome

Cited by 48 publications

References 85 publications

Hyperventilation: A Possible Explanation for Long-Lasting Exercise Intolerance in Mild COVID-19 Survivors?

Hyperventilation: A Possible Explanation for Long-Lasting Exercise Intolerance in Mild COVID-19 Survivors?

Rehabilitering etter covid-19

Post-COVID-19 rehabilitation – a Polish pilot program

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