The long-term effects of DDT exposure on semen, fertility, and sexual function of malaria vector-control workers in Limpopo Province, South Africa

Dalvie, Mohamed Aqiel; Myers, Jonathan E.; Thompson, Mary Lou; Robins, Thomas G.; Dyer, Silke; Riebow, John; Molekwa, Josef; Jeebhay, Mohamed F.; Millar, Robert P.; Kruger, Philip

doi:10.1016/j.envres.2003.09.002

Cited by 73 publications

(42 citation statements)

References 34 publications

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“…Within Minnesota, the levels of pesticides were low for any of the pesticides, no significant associations were found too, but because of the overall results this study is classified in this category. Dalvie et al (2004) evaluated exposure to DDT in workers in South Africa, in relation to sperm quality and sexual function. Exposure was assessed by serum levels of o'p' and p'p' isomers of DDT, DDE, DDD.…”

Section: Studies With Evidence Of An Associationmentioning

confidence: 99%

Pesticide Exposure and Health Related Issues in Male and Female Reproductive System

Sifakis¹,

Mparmpas²,

Tsatsakis³

2011

Pesticides - Formulations, Effects, Fate

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Section: Studies With Evidence Of An Associationmentioning

confidence: 99%

Pesticide Exposure and Health Related Issues in Male and Female Reproductive System

Sifakis¹,

Mparmpas²,

Tsatsakis³

2011

Pesticides - Formulations, Effects, Fate

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“…The milk and its products, which are nutritionally enriched, with superior biological potential and the one without health risks, are usually demanded [1][2][3] which include neurodevelopmental delay [4], reproductive effects [5], preterm & small-for-gestational-age babies [6] and immunotoxicity [7]. The presence of any chemical in milk is a cause for concern and great strides are taken throughout the dairy industry to assure the purity of the milk.…”

Section: Introductionmentioning

confidence: 99%

Quantification of Organochlorine Pesticide Residues in the Buffalo Milk Samples of Delhi City, India

Aslam¹,

Rais²,

Alam³

2013

JEP

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The ill effects of green revolution include residues of extensively used chemical pesticides in various environmental components. The present study was designed to analyze the levels of organochlorine pesticide residues along with chemical composition in buffalo milk samples collected from different localities of Delhi. Milk monitoring can yield information about the kinds and quantities of pesticides in the environment as well as in our daily diet. In this study, the residue of three different organochlorine pesticides, namely Hexachlorocyclohexane (HCH), Dichlorodiphenyltrichloroethane (DDT) and Endosulfan have been reported. Residues of Lindane exceeded the Maximum Residual Limit values in 50% of the samples is a cause of serious concern. The p,p'-DDT was detected in 70% of the samples with p,p'-DDE (dichlorodiphenyldichloroethylene) in 80% of the milk samples of different parts of Delhi state. DDD (Dichlorodiphenyldichloroethane) another metabolite of p,p'-DDT was detected in 65% of the milk samples. The analysis indicates that DDT is the major contaminants in different parts of Delhi state. α and β endosulfan were detected in 35% and 40% of the samples analyzed. The statistical correlation shows no significant correlation between chemical compositions of the samples. The presence of multiple chemicals in virtually all samples of buffalo milk raises new questions about the possible toxicological impacts of chemical mixtures on an infant's developing nervous and immune systems and reproductive organs.

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“…In addition, although there are many reviews arguing that DDT is safe, [8][9][10][11] toxicity data from animal studies and recent epidemiologic studies suggest that there may be previously unrecognized long-term negative health consequences for those exposed to insecticides, particularly DDT, even at the low levels seen with IRS. [12][13][14][15][16][17][18] This finding highlights the need for a synthetic perspective on the effectiveness of IRS in reducing the malaria burden, which can be weighed against potential harmful effects of exposure to those insecticides.…”

Section: Introductionmentioning

confidence: 99%

Reduction of Malaria Prevalence by Indoor Residual Spraying: A Meta-Regression Analysis

Kim

Fedak

Kramer

2012

The American Society of Tropical Medicine and Hygiene

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Abstract. Indoor residual spraying (IRS) has become an increasingly popular method of insecticide use for malaria control, and many recent studies have reported on its effectiveness in reducing malaria burden in a single community or region. There is a need for systematic review and integration of the published literature on IRS and the contextual determining factors of its success in controlling malaria. This study reports the findings of a meta-regression analysis based on 13 published studies, which were chosen from more than 400 articles through a systematic search and selection process. The summary relative risk for reducing malaria prevalence was 0.38 (95% confidence interval = 0.31-0.46), which indicated a risk reduction of 62%. However, an excessive degree of heterogeneity was found between the studies. The meta-regression analysis indicates that IRS is more effective with high initial prevalence, multiple rounds of spraying, use of DDT, and in regions with a combination of Plasmodium falciparum and P. vivax malaria.

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The long-term effects of DDT exposure on semen, fertility, and sexual function of malaria vector-control workers in Limpopo Province, South Africa

Cited by 73 publications

References 34 publications

Pesticide Exposure and Health Related Issues in Male and Female Reproductive System

Pesticide Exposure and Health Related Issues in Male and Female Reproductive System

Quantification of Organochlorine Pesticide Residues in the Buffalo Milk Samples of Delhi City, India

Reduction of Malaria Prevalence by Indoor Residual Spraying: A Meta-Regression Analysis

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