The long‐term impact of <scp>COVID</scp>‐19

Lehman, Cheryl; Green, Theresa; Booth, Jo

doi:10.1111/jocn.16966

Cited by 2 publications

(3 citation statements)

References 17 publications

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“…Although children have a less severe presentation than adults [6], there is evidence that 15-84% of pediatric patients with COVID-19 experience at least one gastrointestinal symptom, including abdominal pain, diarrhea, or vomiting [7]. Several physiopathological mechanisms, including an altered barrier function of the intestinal wall, local inflammation, and SARS-CoV-2-associatedintestinal dysbiosis, are cited as related to these GI manifestations [8].…”

Section: Introductionmentioning

confidence: 99%

“…Both characterized by a disrupted inflammatory response and a pro-inflammatory background, COVID-19 and IBD display a particular connection in terms of disease onset and evolution. Although the understanding of this relationship is still evolving, several studies have shed light on the potential impact of COVID-19 on children with pre-existing IBD as well as on the onset of new pediatric IBD cases [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

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Impact of COVID-19 on Pediatric Inflammatory Bowel Diseases—From Expectations to Reality

Trandafir,

Spoiala,

Ghiga

et al. 2024

JPM

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Viral infections have always been considered a threat to global health, with numerous outbreaks across time. Despite the relative recent experience with coronavirus-associated diseases such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), severe acute respiratory syndrome-2’s (SARS-CoV-2) continuous evolution displays a different behavior. With a tropism for both respiratory and digestive mucosa, coronavirus disease 2019 (COVID-19) and inflammatory bowel disease (IBD) seem to share a particular common background. Current literature offers evidence that viral alteration of the immune system, inflammatory intestinal tissue damage, increased intestinal permeability, incomplete viral clearance with viral antigen persistence, and intestinal dysbiosis, might explain SARS-CoV-2–IBD relationship in terms of etiopathogenesis and evolution. The hyperinflammatory state that both entities have in common explains the lack of success of current IBD therapy, raising the need for new personalized therapeutic options, with better outcomes for IBD and COVID-19 as well. This review aims to summarize the current available data on pediatric IBD evolution, management, and outcomes in the post-COVID period, with an emphasis on the particular aspects of the SARS-CoV-2–IBD relationship in children.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impact of COVID-19 on Pediatric Inflammatory Bowel Diseases—From Expectations to Reality

Trandafir,

Spoiala,

Ghiga

et al. 2024

JPM

View full text Add to dashboard Cite

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“…According to the National Institute for Health and Care Excellence (NICE), post-COVID-19 syndrome is described as symptoms that develop or remain and last longer than 12 weeks following diagnosis [ 4 ]. There are at least 200 symptoms associated with the post-COVID-19 syndrome, including arthralgia, lack of taste and smell, exhaustion, dyspnea, and cognitive decline [ 5 ]. The presence of these symptoms results in varying degrees of functional disability, limiting day-to-day activities [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

The Prevalence and Associated Factors of Post-COVID-19 Fatigue: A Systematic Review and Meta-Analysis

Hu,

Tang,

Gong

et al. 2024

Cureus

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After the coronavirus disease 2019 (COVID-19) pandemic, numerous individuals experienced the enduring consequences of infection. One of the psychological symptoms that patients report most frequently is persistent fatigue, which is also called post-COVID-19 fatigue. This persistent fatigue can prolong recovery time for hospitalized patients and reduce exercise motivation for residents, affecting their health and working conditions. To determine the prevalence and associated factors, we conducted searches in PubMed, Embase, Web of Science, and Cochrane Library, from inception to 27 March 2023, and a total of 38 studies and 17,738 patients were included in this analysis. We analyzed data and estimated publication bias by Egger’s test and funnel plot by STATA 14. We summarized the prevalence of post-COVID-19 fatigue and calculated the pooled OR to determine associated factors. This study revealed that the prevalence of fatigue in post-COVID-19 syndrome was 46.6% (95% CI: 38.5%-54.7%). Being female (OR: 0.40, 95% CI: 0.24-0.56), older age (OR: 0.04, 95% CI: 0.01-0.07), clinical severity (OR: 0.66, 95% CI: 0.24-1.09), the number of acute COVID symptoms (OR: 3.23, 95% CI: 1.83-5.69), preexisting hypertension (OR: 1.24, 95% CI: 1.08-1.42), lung disease (OR: 2.71, 95% CI: 1.07-6.89), and depression (OR: 1.55, 95% CI: 1.01-2.39) were risk factors for post-COVID-19 fatigue. By revealing the association of these factors with fatigue, it can help us to identify and treat post-COVID-19 fatigue early.

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The long‐term impact of COVID‐19

Cited by 2 publications

References 17 publications

Impact of COVID-19 on Pediatric Inflammatory Bowel Diseases—From Expectations to Reality

Impact of COVID-19 on Pediatric Inflammatory Bowel Diseases—From Expectations to Reality

The Prevalence and Associated Factors of Post-COVID-19 Fatigue: A Systematic Review and Meta-Analysis

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