This case report aims to detail the fabrication and implementation of a custom ocular prosthesis for a patient with unilateral congenital anophthalmia. This study highlights the innovative approach, the procedures undertaken, and the significant outcomes achieved. A detailed assessment of the patient's anophthalmic socket was conducted. A custom impression technique was used to fabricate the prosthesis, ensuring optimal fit and aesthetic appearance. The process included impression making, customized prosthesis design, and fitting sessions.The custom ocular prosthesis achieved excellent aesthetic integration, restoring facial symmetry and enhancing the patient's appearance. Follow-up assessments showed satisfactory prosthesis retention, minimal discomfort, and positive psychosocial impacts, including improved self-esteem and social interactions.This case underscores the importance of individualized prosthetic solutions in managing congenital unilateral anophthalmia.