1960
DOI: 10.1056/nejm196001282620401
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The Magnesium-Deficiency Tetany Syndrome in Man

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1962
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Cited by 162 publications
(41 citation statements)
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“…Another reason particularly in patients with a jejunostomy is that salt and water depletion causes secondary hyperaldosteronism, which increases renal magnesium excretion [125,126] . The clinical syndrome of magnesium deficiency in man includes fatigue, depression, jerky and weak muscles, ataxia, athetoid movements, cardiac arrhythmia's and, if severe, convulsions [127][128][129][130] . The occurrence of carpopedal spasm, positive Chvostek and Trousseau's signs generally occur if there is a concomitant hypocalcaemia [128,129,131] .…”
Section: Magnesium Depletionmentioning
confidence: 99%
“…Another reason particularly in patients with a jejunostomy is that salt and water depletion causes secondary hyperaldosteronism, which increases renal magnesium excretion [125,126] . The clinical syndrome of magnesium deficiency in man includes fatigue, depression, jerky and weak muscles, ataxia, athetoid movements, cardiac arrhythmia's and, if severe, convulsions [127][128][129][130] . The occurrence of carpopedal spasm, positive Chvostek and Trousseau's signs generally occur if there is a concomitant hypocalcaemia [128,129,131] .…”
Section: Magnesium Depletionmentioning
confidence: 99%
“…1 The clinical consequences of severe hypomagnesemia include muscle weakness, tetany, convulsions, cardiac arrhythmias and hypotension. [2][3][4][5] Studies have also demonstrated an association between hypomagnesemia and both cardiovascular and non-cardiovascular mortality. 6,7 Magnesium (Mg) has been found to lower inflammation, decrease oxidative stress and diminish endothelial dysfunction -all factors that underlie cardiovascular disease.…”
Section: Introductionmentioning
confidence: 99%
“…On the other hand, there is recurring evidence, since the early 1960s, that a relative or absolute lack of Mg ++ is related to certain neurological conditions such as criptotetany, latent tetany, hyperventilation syndrome and spasmophilia [10][11][12][13][14][15][16][17]. The latter has recently been referred to as the central neuronal hyperexcitability syndrome (NHS) [18,19].…”
Section: Introductionmentioning
confidence: 99%