Anaemia in children remains a significant public health threat. Recent numbers from Ethiopia showed that more than two-thirds of children under the age of 2 years were anaemic. This study aimed to investigate the determinants of anaemia throughout Ethiopia over 11 years, making use of the Ethiopian Demographic and Health Survey (EDHS) rounds 2005, 2011 and 2016. The EDHS made it possible to use data on blood tests and detailed questionnaires among infants and young children. Multivariable logistic regression was applied to assess the association of anaemia and different immediate and underlying determinants. A total of 7,324 children aged 6-23 months were included in the analysis, with prevalences of anaemia being 71% in 2005, 61% in 2011 and 72% in 2016. The following determinants were significantly associated with childhood anaemia throughout the entire period: children younger than 1 year, anaemic mothers and those growing up in pastoralist regions. Risk factors such as diet and infections were consistently not significantly associated with anaemia. Given the tremendous adverse health effects of anaemia in young children, urgent action is needed. Hence, this study recommends nationwide multisectoral interventions targeting pastoralist regions, maternal and child health, screening and treatment of risk groups that could reduce the prevalence of anaemia. K E Y W O R D S anaemia, children aged 6-23 months, determinants, DHS, Ethiopia, prevalence, public health 1 | INTRODUCTION Anaemia remains a significant global health concern with over onequarter of the world's population affected by the condition (Balarajan, Ramakrishnan, Ozaltin, Shankar, & Subramanian, 2011). Developing countries, in particular, Africa and SouthEast Asia, account for over 89% of the global anaemia burden (Kassebaum, 2016; WHO, 2015). Aside from disproportionately affecting these regions, anaemia prevalence differs by age group. In particular, young children under the age of 5 years account for over 47% of the total burden (Balarajan et al., 2011), with one of the highest prevalence existing in Ethiopia (World Health Organization [WHO], 2015). The Ethiopian Demographic and Health Survey (EDHS) 2016 reported that 57% of the children under the age of 5 years were anaemic. Levels were highest in those aged 6-23 months, with 72% of these children having anaemia (Central Statistical Agency/Ethiopia [CSA] and ICF, 2017).