The results of gas-dynamic design of a new flow part of a reactive type high-pressure cylinder (HPC) of the K-300 series condensing steam turbine are presented. The turbine was developed using a comprehensive methodology implemented in the IPMFlow software package. The methodology includes gas-dynamic calculations of various levels of complexity, as well as methods for analytical construction of the spatial shape of the blade rows based on a limited number of parameterized values. The real thermodynamic properties of water and steam were taken into account in 3D calculations of turbulent flows. At the final stage, 3D end-to-end calculations of the HPC, which consists of 18 stages, were carried out. The technology of parallel computing was applied in the said calculations. It is shown that a significant increase in efficiency and power has been achieved in the developed HPC due to the use of reactive type stages with modern smooth blade profiles and monotonic meridional contours.