The Malnutrition of Obesity: Micronutrient Deficiencies That Promote Diabetes

Via, Michael A.

doi:10.5402/2012/103472

Cited by 222 publications

(154 citation statements)

References 95 publications

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“…Furthermore, a comparison of Zn, Cr, Mn, and Mg concentrations in hair between the groups with BMI <25 and BMI >30 showed significant differences, with P less than 0.05 at least. The present results corroborate with those in previous studies (30)(31)(32).…”

Section: Discussionsupporting

confidence: 94%

“…Landmark clinical trials on lifestyle changes in subjects with prediabetes have shown that diet and exercise leading to weight loss consistently reduce the incidence of DM. Reducing excess weight and obesity is the key factor in managing DM more efficiently so that the overall health and general sense of well-being can be improved (32)(33)(34).…”

Section: Discussionmentioning

confidence: 99%

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Quantification of Some Trace Elements in The Scalp Hair of Patients with Type 2 Diabetes Mellitus in Jeddah, Saudi Arabia

Farid¹,

Aboalfaraj²

2016

Med J Islamic World Acad Sci

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Type 2 diabetes mellitus (DM) is one of the major global health challenges of the 21st century. Owing to their diversified metabolic characteristics and functions, various metals such as zinc (Zn), copper (Cu), chromium (Cr), manganese (Mn), iron (Fe), and magnesium (Mg) are considered to be essential for human health. Deficiency of some essential trace elements may lead to the development of DM. The present study aimed to evaluate the contents of Zn, Cu, Cr, Mn, and Mg in the scalp hair samples of patients with type 2 DM from Jeddah (Saudi Arabia). The hair samples were collected from 55 patients with DM aged 45-65 years. Also, 55 age-matched nondiabetic healthy subjects were selected from the same city for a comparative analysis. Zn, Cr, Mn, and Mg levels in hair were found to be significantly lower (P < 0.05) in the group of patients with type 2 DM than in nondiabetic subjects. However, the Cu level in hair was significantly higher (P < 0.05) in patients with type 2 DM than in nondiabetic subjects. The results revealed that hair Cu concentrations in patients with DM were positively related to body mass index (BMI), whereas Zn, Cr, Mn, and Mg concentrations were inversely related to BMI. Finally, the concentrations of these trace elements in the scalp hair and serum samples of patients with DM were compared.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Quantification of Some Trace Elements in The Scalp Hair of Patients with Type 2 Diabetes Mellitus in Jeddah, Saudi Arabia

Farid¹,

Aboalfaraj²

2016

Med J Islamic World Acad Sci

View full text Add to dashboard Cite

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“…Obese patients who have a high caloric intake of nutritionally deficient foods may also be malnournished [15][16][17]. The complication rate in malnourished obese patients was over 10%, which was three times higher than in obese patients with normal nutrition.…”

Section: Discussionmentioning

confidence: 98%

“…Malnutrition should be considered in obese patients who are a growing demographic in developed countries and with a proportional increase in TJA [15,17,31,32]. Obese patients who have a high caloric intake of nutritionally deficient foods may also be malnournished [15][16][17].…”

Section: Discussionmentioning

confidence: 99%

The Effect of Malnutrition on Patients Undergoing Elective Joint Arthroplasty

Huang

Greenky

Kerr

et al. 2013

The Journal of Arthroplasty

167

141

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“…To define malnutrition, most surgeons use serum laboratory values such as albumin concentration and total lymphocyte count. Obese patients are known to have micronutrient deficiencies such as iron and 25-hydroxy vitamin D [11,15,30], but the prevalence and significance of protein malnutrition in obese and non-obese patients undergoing TKA are not well characterized. Furthermore, it is unclear whether obesity and malnutrition are independently associated with adverse perioperative events.…”

Section: Introductionmentioning

confidence: 99%

Hypoalbuminemia is a Better Predictor than Obesity of Complications after Total Knee Arthroplasty: A Propensity Score-Adjusted Observational Analysis

McLawhorn

Padgett

et al. 2017

HSS Journal®: The Musculoskeletal Journal of Hospital for Speci

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Background: Obesity is an established risk factor for complications after total knee arthroplasty (TKA) and is often associated with malnutrition. Questions/Purposes: 1. What is the prevalence of hypoalbuminemia in obese patients undergoing TKA? 2. What is the independent morbidity risk of malnutrition relative to obesity? Methods: TKA cases were identified from the National Surgical Quality Improvement Program from 2005 to 2013. Propensity scores for having preoperative albumin measurements were calculated using demographics, BMI, and modified Charlson Comorbidity Index (CCI). Malnutrition was defined as hypoalbuminemia (<3.5 g/dL). Patients were classified by BMI as follows: non-obese (18.5-29.9), obese I (30-34.9), obese II (35-39.9), or obese III (≥40). Postoperative complications were compared across obesity and nutritional statuses. Multivariable propensity-adjusted logistic regressions were performed to determine associations between malnutrition, obesity, and 30-day outcomes. Results: There were 71,599 cases identified, with 34,800 (48.6%) having albumin measurements. Propensity score adjustment adequately accounted for selection bias, with adjusted p > 0.05 for observable characteristics. Malnutrition prevalence increased with BMI (6.1% in obese III vs. 3.7% in non-obese). With propensity-adjusted multivariable analysis, obese III was the only obesity class associated with any complication, wound complication, and reoperation. Hypoalbuminemia was a stronger and more consistent independent risk factor, for any complication, wound, cardiac, or respiratory complications, and death. Conclusions: Hypoalbuminemia is a more consistent independent predictor of complications after TKA than obesity. Strategies for medical optimization of these conditions should be investigated.

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The Malnutrition of Obesity: Micronutrient Deficiencies That Promote Diabetes

Cited by 222 publications

References 95 publications

Quantification of Some Trace Elements in The Scalp Hair of Patients with Type 2 Diabetes Mellitus in Jeddah, Saudi Arabia

Quantification of Some Trace Elements in The Scalp Hair of Patients with Type 2 Diabetes Mellitus in Jeddah, Saudi Arabia

The Effect of Malnutrition on Patients Undergoing Elective Joint Arthroplasty

Hypoalbuminemia is a Better Predictor than Obesity of Complications after Total Knee Arthroplasty: A Propensity Score-Adjusted Observational Analysis

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