The management and clinical course of testicular seminoma: 15 years' experience at a single institution

Coleman, James M.; Coleman, RE; Turner, A. Robert; Radstone, C. R.; Champion, A.E.

doi:10.1016/s0936-6555(98)80007-1

Cited by 34 publications

(12 citation statements)

References 16 publications

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“…In large single or multi-institutional series, the relapse rate has varied from 0.5% to 5% (Table 4). 19,[23][24][25][26][27] The most common sites of relapse following adjuvant radiotherapy are the mediastinum, lungs and the left supraclavicular fossa. A small proportion of patients, usually with predisposing factors, relapse in the inguinal nodes.…”

Section: Adjuvant Radiotherapymentioning

confidence: 99%

Canadian consensus guidelines for the management of testicular germ cell cancer

Wood

Kollmannsberger

Jewett

et al. 2013

CUAJ

123

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Section: Adjuvant Radiotherapymentioning

confidence: 99%

Canadian consensus guidelines for the management of testicular germ cell cancer

Wood

Kollmannsberger

Jewett

et al. 2013

CUAJ

123

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“…Concernant la radiothé-rapie, les études retrouvent une survie globale de 92 % à 10 ans et 77 % à 20 ans avec une survie spécifique de 99 % à 100 % à 10 ans et de 97 % à 99 % à 20 ans. Le taux de rechute est estimé à 1 %-6,3 % à 10 ans et 2 % à 20 ans [12]. Les résul-tats après chimiothérapie sont également superposables.…”

Section: Discussionunclassified

Surveillance des séminomes testiculaires de stade I : résultats oncologiques sur 20ans

Zores

Mouracadé

Duclos

et al. 2015

Progrès en Urologie

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“…Of 144 patients who had received adjuvant RT, only six (four percent) relapsed, establishing a meaningful difference between the two groups ( P < 0.05). Because of management options after relapses and long‐term follow‐up, the overall survival rate was not found to be different in each group and said to be safe in the long term follow‐up of patients after orchiectomy 14 …”

Section: Discussionmentioning

confidence: 99%

Retrospective analysis of 74 cases of seminoma treated with radiotherapy

Güden

Göktaş²,

Sümer³

et al. 2003

Int J of Urology

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Background : Standard post-orchiectomy radiotherapy (RT) is accepted as a standard management option for stage I seminoma. Methods : Retrospective evaluation of 74 patients with stage I seminoma was performed according to the Royal Marsden staging system. All of the patients underwent RT in the Radiation Oncology Department of Gülhane Military Medical Academy between 1974 and 1995. The median age of patients was 27 years (range, 20-56). Radiotherapy was applied to all of the patients after orchiectomy for adjuvant purposes. Sixty-nine patients underwent RT while five patients who had recurrence received chemotherapy following radiotherapy. Results : After a mean follow-up period of 54 months, the 5-year overall survival rate was 98.61%, which complied with the literature. The disease-free survival rate was 90.54%. According to the World Health Organization toxicity scale, acute enteritis was 9.4% for grade I and 5.4% for grade II, while nausea/vomiting was 36.4% for grade I and 5.4% for grade II. Conclusion : To avoid acute toxicity related to RT, prognostic risk factors should be well-known and patients with low risk factors should be monitored carefully after orchiectomy. RT should be directed to the para-aortic ± ipsilateral pelvic lymph nodes in high risk patients. Although post-orchiectomy RT is a traditional management option for clinical stage I seminoma, the results of RT should be well-known to compare it with other treatment options (e.g. RPLND, adjuvant chemotherapy and surveillance).

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The management and clinical course of testicular seminoma: 15 years' experience at a single institution

Cited by 34 publications

References 16 publications

Canadian consensus guidelines for the management of testicular germ cell cancer

Canadian consensus guidelines for the management of testicular germ cell cancer

Surveillance des séminomes testiculaires de stade I : résultats oncologiques sur 20ans

Retrospective analysis of 74 cases of seminoma treated with radiotherapy

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