2023
DOI: 10.3390/jcm13010166
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The Management of Hepatic Encephalopathy from Ward to Domiciliary Care: Current Evidence and Gray Areas

Daniele Bellafante,
Stefania Gioia,
Jessica Faccioli
et al.

Abstract: Hepatic encephalopathy (HE) is a common complication of advanced liver disease and acute liver failure. It is a condition that features several neuropsychiatric symptoms that affect mortality, morbidity and the quality of patients’ and caregivers’ lives. An HE diagnosis is generally an exclusion diagnosis. Once the patient is admitted to the hospital, clinical examination, blood tests and eventually neuroimaging should be performed with the aim of ruling out other causes of acute brain dysfunction. Moreover, H… Show more

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“…The identification and correction of IDA have been emphasized as an essential part of comprehensive clinical management for CHF patients [8]. In addition to these findings, recent research has delved deeper into the intricacies of iron deficiency in heart failure in which a study on the nuanced relationship between iron metabolism and the pathophysiology of CHF elucidated that impaired iron homeostasis contributes significantly to the progression of heart failure [9]. This expanding body of evidence strongly supports the inclusion of routine assessment for IDA and targeted iron supplementation as a pivotal component of the holistic management of CHF patients, offering symptomatic relief and potential avenues for improving their overall cardiac function and prognosis.…”
Section: Discussionmentioning
confidence: 99%
“…The identification and correction of IDA have been emphasized as an essential part of comprehensive clinical management for CHF patients [8]. In addition to these findings, recent research has delved deeper into the intricacies of iron deficiency in heart failure in which a study on the nuanced relationship between iron metabolism and the pathophysiology of CHF elucidated that impaired iron homeostasis contributes significantly to the progression of heart failure [9]. This expanding body of evidence strongly supports the inclusion of routine assessment for IDA and targeted iron supplementation as a pivotal component of the holistic management of CHF patients, offering symptomatic relief and potential avenues for improving their overall cardiac function and prognosis.…”
Section: Discussionmentioning
confidence: 99%