1968
DOI: 10.1136/pgmj.44.516.803
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The management of myelomatosis

Abstract: SummaryThirty-six out of sixty-two cases of myelomatosis have been treated with melphalan.Platelet counts were used as a guide to dosage early in the course of treatment, after which a more empirical dosage (0-15 mg/kg/ day) was used in 1-week courses given every 12 weeks. Rapid deterioration and death occur in a small number of patients whatever therapy is given.In the group treated with melphalan the median survival time was 25 months, longer than in those treated with radiotherapy or other chemotherapeutic … Show more

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