The management of retroperitoneal sarcoma: The experience of a single institution and a review of the literature

Jihene, F.; Maissa, L.; Mohamed, F.; Dhouha, S.; Rania, Bannour; Mourad, H.S.; Jamel, D.; Afef, K.

doi:10.1016/j.jtumed.2022.07.007

Cited by 2 publications

(1 citation statement)

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“…Liposarcoma is a rare malignancy derived from mesenchymal cells; retroperitoneal liposarcoma (RPLS), which occurs in the retroperitoneal region and is the most common retroperitoneal tumor, accounts for approximately 1% of all malignancies, 25% of all soft tissue sarcomas, and 45% of primary retroperitoneal soft tissue sarcomas (1)(2)(3). RPLS refers to a kind of soft tissue malignant tumor originating from adipose tissue and occurring in the retroperitoneal space.…”

Section: Introductionmentioning

confidence: 99%

Analysis of recurrence and metastasis patterns and prognosis after complete resection of retroperitoneal liposarcoma

Gao,

Ding,

Zhang

et al. 2023

Front. Oncol.

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ObjectiveTo analyze the recurrence and metastasis patterns and prognosis after complete resection of retroperitoneal liposarcoma.MethodsThe clinical postoperative follow-up data and results of patients who underwent complete resection of retroperitoneal liposarcoma from September 10, 2014, to September 8, 2021, at Hebei Medical University hospital were collected retrospectively.ResultsA total of 60 patients with complete resection of retroperitoneal liposarcoma, including 33 cases of retroperitoneal liposarcoma recurrence, 2 cases of liver metastasis, and 1 case of lung metastasis, were included. The results showed that 100% of the recurrent sites were located in the primary region of the tumor, with most recurrences located near the kidney, paracolic sulci, and iliac vessels. Three patients had distant metastasis without obvious recurrence on imaging examination. The pathological type of retroperitoneal liposarcoma, Ki67 expression, and presence of serum albumin were risk factors for recurrence and metastasis after complete resection of retroperitoneal liposarcoma. The malignancy and Ki67 expression were independent risk factors for recurrence and metastasis as well as for overall survival of patients undergoing complete resection of retroperitoneal liposarcoma.ConclusionComplete resection remains the most effective method to treat retroperitoneal liposarcoma. Patients with pathological types of retroperitoneal liposarcoma showing dedifferentiation, pleomorphism, mixed type, and high Ki67 expression should be closely monitored and observed after complete resection, especially for imaging changes in the primary tumor area.

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Section: Introductionmentioning

confidence: 99%