The Mathematical Treatment of Metabolic Processes

Branson, Herman

doi:10.1007/978-3-642-49761-2_19

Radioactive Isotopes in Physiology Diagnostics and Therapy / Künstliche Radioaktive Isotope in Physiologie Diagnostik Und Thera 1961

DOI: 10.1007/978-3-642-49761-2_19

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The Mathematical Treatment of Metabolic Processes

Herman Branson¹

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1974

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References 120 publications

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Tracer Kinetic Model Analysis of Potassium Uptake by Dissociated Nerve Cell Cultures: Glial‐neuronal Interrelationship

Latzkovits¹,

Sensenbrenner

Mandel³

1974

Journal of Neurochemistry

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Potassium transport in dissociated nerve cell cultures has been studied by analysing 86Rb and ' : K uptake. For this purpose cultures prepared from cerebral hemispheres of both 8-and 14-day-old chick embryos were used in short-term experiments. The potassium pool is in the steady-state in all the cultures. The 86Rb is taken up more rapidly that 42K; however the ratio of amounts of 86Rb and 42K incorporated is constant with time and under different conditions. The run of kinetic curves of uptake has been studied by tracer kinetic model analysis. As a result of this analysis a glial-neuronal interrelationship in transport has been suggested. Furthermore, it was shown that not only glial cells but neurons also take up potassium directly from the medium. Comparing the incorporated amounts in different cultures, a decreased uptake can be seen where glial cells prevail. The significance of this fact is discussed.

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Tracer Kinetic Model Analysis of Potassium Uptake by Dissociated Nerve Cell Cultures: Glial‐neuronal Interrelationship

Latzkovits¹,

Sensenbrenner

Mandel³

1974

Journal of Neurochemistry

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show abstract

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The Mathematical Treatment of Metabolic Processes

Cited by 1 publication

References 120 publications

Tracer Kinetic Model Analysis of Potassium Uptake by Dissociated Nerve Cell Cultures: Glial‐neuronal Interrelationship

Tracer Kinetic Model Analysis of Potassium Uptake by Dissociated Nerve Cell Cultures: Glial‐neuronal Interrelationship

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